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90-120 / 1000+ resultsresearch Hormonal and Genetic Etiology of Male Androgenetic Alopecia
![Finasteride blocks progesterone synthesis in MA-10 Leydig tumor cells.](/images/research/9c1cc72d-310c-4a22-a1ef-bff516a51cf2/small/2014.jpg)
research Finasteride blocks progesterone synthesis in MA-10 Leydig tumor cells.
Finasteride blocks progesterone production in specific tumor cells, potentially causing side effects.
![Development and homeostasis of the sebaceous gland](/images/research/727feb97-4c91-4037-b57c-0f54dd71592d/small/14639.jpg)
research Development and homeostasis of the sebaceous gland
The document concludes that understanding the sebaceous gland's development and function is key to addressing related skin diseases and aging effects.
![Drug discovery for alopecia: gone today, hair tomorrow](/images/research/7e4bda3e-56f8-48a2-989b-41805c4beb6b/small/3558.jpg)
research Drug discovery for alopecia: gone today, hair tomorrow
Topical drugs and near-infrared light therapy show potential for treating alopecia.
![Androgenetic alopecia in men aged 40-69 years: prevalence and risk factors](/images/research/3960571c-ed58-42ce-ad12-efc87acb003a/small/2498.jpg)
research Androgenetic alopecia in men aged 40-69 years: prevalence and risk factors
Hair loss increases with age; alcohol raises risk, more female partners lowers it.
![Diet in dermatology: Revisited](/images/research/0f771585-14e3-4220-973a-00fe1b125acf/small/24751.jpg)
research Diet in dermatology: Revisited
Certain diets can affect skin conditions, but more research is needed to understand these relationships fully.
![Molecular and spatial design of early skin development](/images/research/25c4d970-5084-4d2b-a716-ddef74281952/small/30437.jpg)
research Molecular and spatial design of early skin development
The research reveals how early embryonic mouse skin develops from simple to complex structures, identifying various cell types and their roles in this process.
research Multipotent Nestin-Positive Stem Cells Reside in the Stroma of Human Eccrine and Apocrine Sweat Glands and Can Be Propagated Robustly In Vitro
Human sweat glands have a type of stem cell that can grow well and turn into different cell types.
![Endocrinology](/images/research/c5dccbe8-dab2-4002-8520-c3cea99fd333/small/12995.jpg)
research Endocrinology
The document concludes that inflammation markers can be used in diabetes, vitamin D3 affects immune pathways, hyperthyroidism changes hormone levels, androgen levels help diagnose Adrenocortical Carcinoma, erectile dysfunction is linked to diabetes, hypogonadism is common in HIV-infected males, and hormones can be biomarkers for various conditions.
research The skin as an endocrine organ
The skin produces and processes hormones, affecting both local and overall body functions.
![Androgen receptor activation integrates complex transcriptional effects in osteoblasts, involving the growth factors TGF-β and IGF-I, and transcription factor C/EBPδ](/images/research/7b17d172-b07a-41b8-988f-d85795ccd205/small/35628.jpg)
research Androgen receptor activation integrates complex transcriptional effects in osteoblasts, involving the growth factors TGF-β and IGF-I, and transcription factor C/EBPδ
DHT affects bone growth by altering gene activity in osteoblasts, potentially complicating steroid use.
![Identification of differentially expressed genes affecting hair and cashmere growth in the Laiwu black goat by microarray](/images/research/aca5abc4-b79f-4cdf-9f59-2e81db78aa5c/small/29127.jpg)
research Identification of differentially expressed genes affecting hair and cashmere growth in the Laiwu black goat by microarray
Specific genes influence hair and cashmere growth in Laiwu black goats.
![Compendium of polycystic ovarian syndrome and its relevance in glycation and diabetes](/images/research/c90d6c26-8ce0-4e47-b9c3-3143b873cbe7/small/20726.jpg)
research Compendium of polycystic ovarian syndrome and its relevance in glycation and diabetes
PCOS is linked to diabetes and insulin resistance, and managing AGEs may help treat related symptoms.
![Type A insulin resistance syndrome due to a novel heterozygous c.3486_3503del (p. Arg1163_Ala1168del) INSR gene mutation in an adolescent girl and her mother](/images/research/57cd6865-fdd1-42a9-b30a-3e0605900e2f/small/36861.jpg)
research Type A insulin resistance syndrome due to a novel heterozygous c.3486_3503del (p. Arg1163_Ala1168del) INSR gene mutation in an adolescent girl and her mother
A new gene mutation causes insulin resistance in a girl and her mother.
![Transforming growth factor-β in stem cells and tissue homeostasis](/images/research/4d38f480-144e-4334-af2c-4d1b50204625/small/19469.jpg)
research Transforming growth factor-β in stem cells and tissue homeostasis
TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.
research The Role of MicroRNA, Long Non-Coding RNA and Circular RNA in the Pathogenesis of Polycystic Ovary Syndrome: A Literature Review
MicroRNAs could be key biomarkers and therapeutic targets for PCOS.
![Use of oral contraceptives in the management of acne](/images/research/f8315bdb-54b1-4617-9311-0ff16b38981e/small/28070.jpg)
research Use of oral contraceptives in the management of acne
Birth control pills with low-dose estrogen and antiandrogenic progestins can effectively treat acne.
![Regenerative Medicine of Epidermal Structures](/images/research/15b2f64d-a2a9-4dc3-b0fb-06d107dc3121/small/26095.jpg)
research Regenerative Medicine of Epidermal Structures
New treatments for skin and hair repair show promise, but further improvements are needed.
![Multiple Roles of Integrin-Linked Kinase in Epidermal Development, Maturation and Pigmentation Revealed by Molecular Profiling](/images/research/c2af2390-b135-47a4-9924-e45cb5ca3a31/small/19842.jpg)
research Multiple Roles of Integrin-Linked Kinase in Epidermal Development, Maturation and Pigmentation Revealed by Molecular Profiling
ILK is essential for skin development, pigmentation, and healing.
![Wnt signaling activation: targets and therapeutic opportunities for stem cell therapy and regenerative medicine](/images/research/1e188113-e96f-401f-8bcf-778820fc7f6d/small/22878.jpg)
research Wnt signaling activation: targets and therapeutic opportunities for stem cell therapy and regenerative medicine
Wnt activation shows promise for regenerative medicine but requires selective targeting to minimize risks like cancer.
![TGF‐β<sub>2</sub> is specifically expressed in human dermal papilla cells and modulates hair folliculogenesis](/images/research/7886a053-45d8-414f-9112-1031027daae3/small/30923.jpg)
research TGF‐β2 is specifically expressed in human dermal papilla cells and modulates hair folliculogenesis
TGF-β2 plays a key role in human hair growth and development.
![Prolactin: an emerging force along the cutaneous–endocrine axis](/images/research/bd30807e-697c-4244-9a83-ca15386d6c40/small/24698.jpg)
research Prolactin: an emerging force along the cutaneous–endocrine axis
Prolactin may play a significant role in skin and hair health and could be a target for treating skin and hair disorders.
![The Endocrine Function of the Skin: An Analytical Narrative](/images/research/e52ca5a2-471a-4b9b-aec7-e13661bd5ecb/small/29905.jpg)
research The Endocrine Function of the Skin: An Analytical Narrative
The skin acts like an endocrine organ, producing hormones that affect various body functions and skin health, and understanding this can lead to new treatments.
![Mutant laboratory mice with abnormalities in hair follicle morphogenesis, cycling, and/or structure: annotated tables](/images/research/3555e7a8-9878-49b5-8e4e-a57355cf9617/small/35688.jpg)
research Mutant laboratory mice with abnormalities in hair follicle morphogenesis, cycling, and/or structure: annotated tables
Mutant mice help researchers understand hair growth and related genetic factors.
![Immunological and Metabolic Causes of Infertility in Polycystic Ovary Syndrome](/images/research/219b6a2d-d8ec-4f7e-ac9c-8a9bb5438a4d/small/16602.jpg)
research Immunological and Metabolic Causes of Infertility in Polycystic Ovary Syndrome
PCOS causes infertility mainly due to hormonal imbalances, insulin resistance, and chronic inflammation.
![Obesity and the Polycystic Ovary Syndrome](/images/research/7927dfd4-8f53-4b6b-ad13-cf263b718647/small/15148.jpg)
research Obesity and the Polycystic Ovary Syndrome
Obesity worsens Polycystic Ovary Syndrome symptoms, and weight loss is a key treatment.
![Honokiol protects skin cells against inflammation, collagenolysis, apoptosis, and senescence caused by cigarette smoke damage](/images/research/b292b45d-9baa-477a-bddf-907fc60da879/small/18294.jpg)
research Honokiol protects skin cells against inflammation, collagenolysis, apoptosis, and senescence caused by cigarette smoke damage
Honokiol helps protect skin from damage and aging caused by cigarette smoke.
![SOX9 in organogenesis: shared and unique transcriptional functions](/images/research/f4841a99-c338-4f7b-a23e-13b9af751b3f/small/19161.jpg)
research SOX9 in organogenesis: shared and unique transcriptional functions
SOX9 is essential for the development of various organs and hair follicles.
![Single-Cell Transcriptomics Reveals the Molecular Anatomy of Sheep Hair Follicle Heterogeneity and Wool Curvature](/images/research/1f13a8a4-38a5-4318-8f6a-732b24b8cc8f/small/30607.jpg)
research Single-Cell Transcriptomics Reveals the Molecular Anatomy of Sheep Hair Follicle Heterogeneity and Wool Curvature
The research identified genes that explain why some sheep have curly wool and others have straight wool.