Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study suggests that managing sleep disorders, particularly those involving difficulty initiating sleep, may benefit from dietary interventions that reduce proinflammatory nutrients and increase anti-inflammatory nutrients.

In this study, Carthamus caeruleus root juice exhibited in vitro anti-inflammatory effects by stabilizing human erythrocyte membranes and inhibiting albumin denaturation, as well as showing potential inhibition of COX-2 through in silico analysis; however, further research is needed to confirm efficacy and mechanisms.

This review consolidates various rational design strategies for nanozymes, emphasizing the mechanisms needed for precise design and exploring their applications in treating inflammatory diseases, diagnosing diseases, and environmental uses, while also discussing the challenges and future prospects in this emerging field.

Bhamrung-Lohit may help with inflammation and oxidation.

Personalized medicine is important for treating skin disorders, with new treatments and connections to hormones and genetics being explored.

This study suggests that BTP levels in cerebrospinal fluid might help diagnose CIDP and predict therapy response but require validation in larger cohorts.

This study found that Botryococcus terribilis ethanol extract significantly reduced inflammation markers in LPS-stimulated RAW264 cells, potentially via Axl inhibition and alteration of immune-related gene expression.

This review discusses hair loss treatments with natural compounds, noting their good safety profile but highlighting insufficient peer-reviewed data to support their effectiveness.

This study reviews advances in targeted therapies for moderate-severe dermatological conditions like plaque psoriasis and atopic dermatitis, reporting on newly approved treatments and highlighting the need for further innovations in managing rare inflammatory skin diseases through emerging laboratory techniques and trials.

This review highlights the role of the brain–gut–skin axis in systemic inflammatory skin conditions, revealing potential interventions like microbiome-directed treatments and integrative therapies, though emphasizes the need for more robust clinical validation.

This study found that Dex-loaded hyaluronic acid hydrogel microneedles significantly reduced pain in an acute inflammatory visceral pain model without sedation, suggesting a promising and patient-friendly alternative to intravenous delivery.

Fucoidan may help regrow hair and reduce inflammation in hair loss.

Monocyte-derived dendritic cells play a key role in UVB-induced skin sensitivity and inflammation.

This study examines the role of immune phenotypes and cytokines in the development of pathological scars, providing insights that may aid in early identification and treatment strategies for these scars.

In this study, researchers reported significantly higher serum calprotectin levels in alopecia areata patients compared to controls and that these levels were associated with the disease's severity, type, duration, and nail involvement, suggesting calprotectin as a potential marker for inflammation in these patients.

This study explored new molecular structures as potential COVID-19 treatments, identifying a compound called Hit15 that inhibited viral infection in lab settings and reduced inflammation markers in human neutrophils, suggesting further development is warranted.

This research paper reviews the mechanisms and management of non-biologic immunosuppressive drugs used in dermatology, highlighting their safety profiles and handling during pregnancy, breastfeeding, and vaccination, but does not report specific results on these aspects.

This review highlights the crucial role of histone modification in the pathogenesis and treatment of chronic inflammatory skin diseases, and explores therapeutic strategies targeting these epigenetic changes to improve management of conditions such as psoriasis and atopic dermatitis.

This study found that long-COVID symptoms in children with multisystem inflammatory syndrome did not differ significantly across SARS-CoV-2 variants, with factors like age being more impactful.

This study found that patients with alopecia areata had higher levels of ESR, CRP, and mean platelet volume compared to controls, and that these markers, along with the neutrophils to lymphocytes ratio, were associated with increased disease severity.

This study found that both reflectance confocal microscopy and optical coherence tomography can visualize detailed hair follicle abnormalities in various skin disorders, but larger, higher-quality studies are needed for clinical implementation.

This study observed that a tacrolimus solution (0.1%) applied to the scalp was effective and well-tolerated for treating inflammatory scalp conditions, with 72.7% of patients showing an excellent response after 2 months of treatment, which persisted after 6 months.

This study found that keratin 7 protein expression increased in colon cancer epithelial-derived cells when treated with neutrophil and macrophage conditioned media, suggesting immune cell-derived factors may influence keratin expression.

PDE inhibitors, especially PDE4 inhibitors like apremilast, are effective for certain inflammatory skin conditions but have side effects and can be costly.

In scalded rats, this study found that early melatonin administration may reduce oxidative stress and inflammation, thus protecting hair follicle cells after severe burns.

This review summarizes the dermoscopic structures associated with infectious and inflammatory skin conditions and hair disorders in children but reports no new clinical results.

This review discusses the dermatological adverse events from immunosuppressive and anti-TNF therapy in IBD, finding increased risks of non-melanoma skin cancer and other skin conditions, and recommends regular cancer screening.

This review discusses the complex causes and treatment challenges of chronic inflammatory skin diseases, emphasizing the need for biomarkers to predict treatment responses; it reports no new clinical results.

In this mouse study, the researchers found that the monoclonal antibody ME1 causes hair follicle inflammation by up-regulating TNFα, which can be reduced by TNFα and interleukin-1 inhibitors.

This study observed that in vitro exposure to dihydrotestosterone worsened COVID-19 spike protein-induced endothelial injury, while spironolactone showed potential in reducing this effect, suggesting a rationale for further evaluation in treating COVID-19.