Long-COVID Symptoms After Multisystem Inflammatory Syndrome in Children During Different Pandemic Waves

    January 2024 in “ Pediatria Polska ”
    Katarzyna Ptak, Marta Olszewska, Anna Olchawa-Czech, Aleksandra Wietecha, Kornelia Kukla, Marta Cisowska, Weronika Nedza, Małgorzata Czuba, Przemko Kwinta, Izabela Szymońska
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    Studysummary This study found that long-COVID symptoms in children with multisystem inflammatory syndrome did not differ significantly across SARS-CoV-2 variants, with factors like age being more impactful. Our plain-language summary of this paper — not a Tressless recommendation.
    This study evaluated long-term non-cardiac complications of multisystem inflammatory syndrome in children (MIS-C) caused by different SARS-CoV-2 variants. It included 116 patients from the Children's Hospital of Krakow. The study found that the frequency and variation of long-COVID symptoms did not significantly differ between the Original/Alpha, Delta, and Omicron variant groups, except for higher fatiguability/weakness in the Original/Alpha group during the 4-12-week follow-up. Older age was identified as an independent factor for long-COVID, rather than the specific variant. Despite a high incidence of long-COVID symptoms, long-term follow-up showed above-average quality of life scores, suggesting an overdiagnosis of non-specific symptoms, with quality of life after MIS-C being comparable to the general pediatric population.
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