Non-Biologic Immunosuppressive Drugs for Inflammatory and Autoimmune Skin Diseases

The document provides a comprehensive review of non-biologic immunosuppressive drugs used for treating inflammatory and autoimmune skin diseases, such as methotrexate, mycophenolate mofetil, azathioprine, cyclosporine, dapsone, glucocorticoids, and hydroxychloroquine. It emphasizes the importance of understanding these drugs' pharmacokinetics, adverse effects, and interactions, particularly during pregnancy, breastfeeding, and vaccination. Key points include the need for regular monitoring to manage adverse effects like gastrointestinal issues, myelosuppression, hepatotoxicity, and the importance of patient compliance and risk management. The document also highlights the necessity of careful pre-treatment evaluations and ongoing monitoring to ensure patient safety and effective treatment outcomes.