3 citations
,
April 2009 in “PubMed” This study suggests that early administration of melatonin may reduce oxidative stress and apoptosis in hair follicle cells of scalded rats.
52 citations
,
January 2005 in “International journal of experimental pathology” This study suggests that melatonin may have a radioprotective role against X-ray-induced skin damage in rats, as evidenced by milder injury markers in pretreated animals.
15 citations
,
November 2018 in “Current radiopharmaceuticals” This study found that melatonin, when administered to Wistar rats prior to and after radiation exposure, reduced oxidative stress markers and histopathological damage in skin tissue compared to radiation alone, suggesting it may effectively prevent and treat radiation-induced skin injury.
160 citations
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July 2008 in “Experimental dermatology” This review discusses the protective effects and mechanisms of melatonin in skin and suggests potential therapeutic applications in cutaneous medicine, reporting no new clinical findings.
32 citations
,
January 2022 in “International Journal of Molecular Sciences” This review discusses the impact of melatonin and its metabolites on skin aging, summarizing how they may serve as "aging neutralizers" through their anti-oxidative and anti-inflammatory properties, but reports no new clinical results.