research The Topography of Fibrous Scaffolds Modulates the Paracrine Function of Adipose-Derived Mesenchymal Stem Cells in the Regeneration of Skin Tissues
The shape of fibrous scaffolds can improve how stem cells help heal skin.
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research CD80CD86 Deficiency Disrupts Regulatory CD4+FoxP3+ T Cell Homeostasis and Induces Autoimmune-Like Alopecia
CD80CD86 deficiency causes hair loss by disrupting regulatory T cells.
research Fructose-1,6-Bisphosphate Aldolase A Levels Decrease in Hair Keratinocytes During Androgenetic Alopecia
ALDOA levels drop in hair cells during hair loss.
research Disrupted Cholesterol Biosynthesis and Hair Follicle Stem Cell Impairment in the Onset of Alopecia
Disrupted cholesterol production impairs hair follicle stem cells, leading to hair loss.
research Dysfunction of Hair Follicle Mesenchymal Progenitors Is Associated with Age-Related Hair Loss
Age-related hair loss is linked to the decline and dysfunction of hair follicle stem cells.
research Would You Recognize This Lesion as a Gumma Syphilitica?
LED light helps hair follicle cells grow and prevents them from dying by activating certain cell pathways.
research Wnt/B-Catenin and ERK Pathway Activation: The Possible Mechanism of Various Light-Emitting Diode Light Regulates the Proliferation of Human Outer Root Sheath Cells
LED light helps human hair root cells grow and prevents them from dying by activating specific growth pathways.
research Stem Cell Secretome as a New Booster for Regenerative Medicine
Stem cells help repair tissue mainly by releasing beneficial substances, not by replacing damaged cells.
research New Investigational Drugs for Androgenetic Alopecia
Possible new treatments for common hair loss include drugs, stem cells, and improved transplants.
research The Bright Side of Fibroblasts: Molecular Signature and Regenerative Cues in Major Organs
Fibroblasts, cells usually linked to tissue repair, also help regenerate various organs and their ability decreases with age. Turning adult fibroblasts back to a younger state could be a new treatment approach.
research Idiopathic CD4+ T-Lymphocytopenia
ICL is a condition with low CD4+ T cells like AIDS but not caused by HIV, and normal CD4+ T cell counts may vary between men and women.
research Adaptive Gelatin Microspheres Enhanced Stem Cell Delivery and Integration With Diabetic Wounds to Activate Skin Tissue Regeneration
Gelatin microspheres with stem cells speed up healing in diabetic wounds.
research Keratin Function and Regulation in Tissue Homeostasis and Pathogenesis
Keratin is crucial for keeping skin cells healthy and its changes can lead to diseases and affect cell behavior.
research A Mouse Model for Studying Stem Cell Effects on Regeneration of Hair Follicle Outer Root Sheaths
The study found that stem cells and neutrophils are important for regenerating hair follicle structures in mice.
research Mesenchymal Stem Cell Secretome: Toward Cell-Free Therapeutic Strategies in Regenerative Medicine
The secretions of mesenchymal stem cells could be used for healing without using the cells themselves.
research Inhibition of β-Catenin Signaling in Dermal Fibroblasts Enhances Hair Follicle Regeneration During Wound Healing
Blocking β-catenin in skin cells improves hair growth during wound healing.
research A Novel Therapeutic Paradigm for Patients with Extensive Alopecia Areata
New treatments targeting immune pathways show promise for severe hair loss but need more research for safety and effectiveness.
research Type I Keratin 17 Protein Is Phosphorylated on Serine 44 by p90 Ribosomal Protein S6 Kinase 1 in a Growth- and Stress-Dependent Fashion
Keratin 17 is modified by RSK1 in response to growth and stress, affecting skin growth and stress response.
research Transient Stimulation of TRPV4-Expressing Keratinocytes Promotes Hair Follicle Regeneration in Mice
Activating TRPV4 in skin cells helps regrow hair in mice, possibly offering a treatment for hair loss.
research Dynamic Morphogen-p63 Chromatin Interactions That Guide Epigenetic Changes and p63 Activity in Surface Ectoderm Commitment
The study found that p63 needs signals from morphogens to help skin cells differentiate properly.
research Silk-Inspired In Situ Hydrogel with Enhanced Anti-Tumor Immunity for Photodynamic Therapy in Melanoma and Infected Wound Healing
The silk fibroin-based hydrogel shows promise for treating melanoma and healing infected wounds by killing tumor cells and bacteria, and supporting skin recovery.
research FOXN1 Deficient Nude Severe Combined Immunodeficiency
FOXN1 gene mutations cause a rare, severe immune disease treatable with cell or tissue transplants.
research Vitamin D Increases Expression of Cathelicidin in Cultured Sebocytes
Vitamin D boosts a specific protein in skin cells linked to hair follicles.
research Extra Virgin Olive Oil as Nutritional Therapeutic Immune Enhancer
Extra virgin olive oil may boost the immune system and help fight infections like COVID-19.
research Multi-Scale Spatial Mapping of Cell Populations Across Anatomical Sites in Healthy Human Skin and Basal Cell Carcinoma
The research created a detailed map of skin cells, showing that certain cells in basal cell carcinoma may come from hair follicles and could help the cancer grow.
research Pathophysiology of Behçet's Disease
Behçet's Disease may be caused by genetic and environmental factors leading to abnormal immune responses, and stress management and new treatments could improve patient outcomes.
research Establishment of Keratinocyte Cell Lines from Human Hair Follicles
Scientists created keratinocyte cell lines from human hair that can differentiate similarly to normal skin cells, offering a new way to study skin biology and diseases.
research Central Centrifugal Cicatricial Alopecia Amalgamated with Alopecia Areata: Immunologic Findings
The patient with both scarring and non-scarring hair loss showed complex immune reactions and improved with steroid treatment.
research The Population Dynamics of Cancer: A Darwinian Perspective
Cancer development is like natural selection, involving mutated cells and environmental factors.
research The Changing Landscape of Alopecia Areata: The Translational Landscape
New treatments for hair loss are showing promise due to better understanding of genetics and the immune system.