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Tofacitinib regrew hair in a man with total hair loss but raised cytokine levels, needing more research on possible side effects.

Alopecia areata severity and treatment response are linked to specific cytokine levels.

Alopecia areata involves complex immune and genetic factors, with potential treatment targets identified, but more research is needed.

Radiation therapy damages skin structure and immune function, causing inflammation and potential hair loss.

Tofacitinib improved hair loss and skin symptoms in a patient after secukinumab caused hair loss.

Type 3 Innate Lymphoid Cells help maintain skin health and balance, and are involved in skin diseases and healing.

Faulty Notch signalling may cause hair follicle changes and inflammation in hidradenitis suppurativa.

Treg cell-based therapies might help treat hair loss from alopecia areata, but more research is needed to confirm safety and effectiveness.

Eating a high-fat fish oil diet caused mice to lose hair due to a specific immune cell activity in the skin linked to a protein called E-FABP.

Innate lymphoid cells help control skin bacteria by regulating sebaceous glands.

A new carrier improves skin delivery of tofacitinib for treating inflammatory skin diseases.

SH-MSCs gel can effectively treat alopecia by increasing IL-10 and decreasing TNF-α gene expression.

IL-33 is linked to hair follicle damage in psoriasis and could be a treatment target for hair loss in this condition.

IL-17C is important in inflammatory skin diseases and could be a target for treatment.

TLR3 signaling enhances the immunosuppressive properties of human periodontal ligament stem cells.

NF-κB signaling is crucial in many diseases and can be targeted for new treatments.

Wnt5a may contribute to psoriasis by reducing skin cell growth, blocking skin cell maturation, and increasing inflammation.

Switching from adalimumab to ixekizumab improved a patient's psoriasis and reversed hair whitening.

Melatonin improves cashmere goat hair quality by increasing follicles and reducing skin aging.

Tumor suppressors help control inflammation in cancer and restoring their function could lead to new treatments.

Acne is linked to inflammation and insulin resistance, and is associated with various syndromes that require different treatments.

Some wound-healing cells can turn into fat cells around new hair growth in mice.

RANK is a key target in breast cancer treatment due to its role in tumor growth and bone metastasis.

Oral tofacitinib shows promise in treating atopic dermatitis and alopecia areata, but only slight improvement in vitiligo.

New treatments targeting T-cell pathways are needed for better alopecia areata management.

Activating TRPA1 reduces scarring and promotes tissue regeneration.

Jagged-1 in skin Tregs is crucial for timely wound healing by recruiting specific immune cells.

People with atopic dermatitis have more CD4+ T cells that respond to a certain bacterial lipid, which may play a role in the skin condition's inflammation.

Alopecia areata is an autoimmune condition causing hair loss, linked to genetic factors and immune system issues, with no cure yet.

The JAK/STAT pathway is important in cell processes and disease, and JAK inhibitors are promising for treating related conditions.