Adipokines in the Skin and Dermatological Diseases

The document reviewed the role of adipokines in skin and dermatological diseases, highlighting their involvement in inflammation, metabolic processes, and various skin conditions. Adipokines such as leptin, adiponectin, visfatin, and chemerin were shown to influence immune responses, wound healing, and tumor development. Leptin enhanced pro-inflammatory responses and was linked to acne and androgenetic alopecia, while adiponectin promoted hair growth and had anti-inflammatory effects. The review also discussed the potential of targeting adipokine pathways for therapeutic purposes in treating conditions like psoriasis, atopic dermatitis, and melanoma, emphasizing the complex interplay between adipokines and skin health.