Leptin and the Skin: A New Frontier

    July 2009 in “ Experimental Dermatology ”
    Burkhard Pöeggeler, Carla Schulz, Miguel A. Pappolla … Ralf Paus
    Studysummary This review discusses the role of leptin in skin biology and pathology, highlighting its potential in enhancing skin regeneration, hair cycle progression, and wound healing, but reports no new clinical results.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 10

    1. Human Female Hair Follicles Are a Direct, Nonclassical Target for Thyroid-Stimulating Hormone Journal of Investigative Dermatology · 2008
    2. Thyroid Hormones Directly Alter Human Hair Follicle Functions: Anagen Prolongation and Stimulation of Both Hair Matrix Keratinocyte Proliferation and Hair Pigmentation The Journal of Clinical Endocrinology & Metabolism · 2008
    3. L-Carnitine-L-Tartrate Promotes Human Hair Growth In Vitro Experimental Dermatology · 2007
    4. Impact of Stat3 Activation Upon Skin Biology: A Dichotomy of Its Role Between Homeostasis and Diseases Journal of Dermatological Science · 2007
    5. Human Scalp Hair Follicles Are Both a Target and a Source of Prolactin, Which Serves as an Autocrine and/or Paracrine Promoter of Apoptosis-Driven Hair Follicle Regression American Journal of Pathology · 2006
    6. Corticotropin-Releasing Hormone and the Skin Frontiers in bioscience · 2006
    7. Characterization and Isolation of Stem Cell-Enriched Human Hair Follicle Bulge Cells ˜The œJournal of clinical investigation/˜The œjournal of clinical investigation · 2005
    8. Human Follicular Papilla Cells Carry Out Non-Adipose Tissue Production of Leptin Journal of Investigative Dermatology · 2001
    9. Tissue Regeneration: Hair Follicle as a Model Journal of Investigative Dermatology Symposium Proceedings · 2001
    10. Two Distinct Signaling Pathways in Hair Cycle Induction: Stat3-Dependent and Independent Pathways Proceedings of the National Academy of Sciences of the United States of America · 2000