Tissue Regeneration: Hair Follicle as a Model

    Shigetoshi Sano, Kunihiko Yoshikawa, Satoshi Itami, Junji Takeda
    Studysummary This study found that Stat3 removal in keratinocytes of mice impairs healing and disrupts the normal hair cycle, leading to skin ulcers and hair loss as they age.
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    Research cited in this study 7

    1. Two Distinct Signaling Pathways in Hair Cycle Induction: Stat3-Dependent and Independent Pathways Proceedings of the National Academy of Sciences of the United States of America · 2000
    2. Involvement of Follicular Stem Cells in Forming Not Only the Follicle but Also the Epidermis Cell · 2000
    3. Delayed Wound Healing in Keratin 6a Knockout Mice Molecular and Cellular Biology · 2000
    4. Specific Inhibition of Hair Follicle Formation by Epidermal Growth Factor in an Organ Culture of Developing Mouse Skin Developmental Biology · 1997
    5. Growth Factors in Hair Organ Development and the Hair Growth Cycle Dermatologic Clinics · 1996
    6. Regulation of Hair Follicle Development: An In Vitro Model for Hair Follicle Invasion of Dermis and Associated Connective Tissue Remodeling Journal of Investigative Dermatology · 1993
    7. The Secret Life of the Hair Follicle Trends in genetics · 1992

    Related research 4

    1. Preliminary Studies of Hair Follicle Regeneration by Injections of Epidermal Stem Cells and Dermal Papilla Cells into Nude Mice Cell and Tissue Banking · 2020
    2. Impaired Keratinocyte Proliferative And Clonogenic Potential In Transgenic Mice Overexpressing 14-3-3σ In The Epidermis Journal of Investigative Dermatology · 2011
    3. Tissue Regeneration: Hair Follicle as a Model Journal of Investigative Dermatology Symposium Proceedings · 2001
    4. Mrp3, A Mitogen-Regulated Protein/Proliferin Gene Expressed In Wound Healing And In Hair Follicles Endocrinology · 2001