Higher Plasma Leptin Is Associated With Higher Risk Of Androgenetic Alopecia In Men

    April 2017 in “ Experimental Dermatology ”
    Chao Yang, Pei-Lun Chung, Liyu Lin, Michael Hughes, Yau Sheng Tsai
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    TLDR More plasma leptin means higher baldness risk in men.
    The study found that higher levels of plasma leptin were associated with a higher risk of androgenetic alopecia (AGA) in men, independent of age and obesity. The study suggests that leptin may play a role in the development of AGA in men. The study also found that plasma levels of TGF-B1 were higher in AGA versus non-AGA subjects, suggesting a systemic effect from circulating factors implicated in the pathogenesis of AGA. However, the study had a relatively small number of subjects, which made the power of group stratification and regression analysis less effective.
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