Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This review discusses the renaming of Polycystic Ovary Syndrome to Polyendocrine Metabolic Ovarian Syndrome, reflecting its broader recognition as a multisystem metabolic-endocrine disorder, and reports no new clinical results.

This case report details a rare large epidermal cyst over the sacrumcoccygeal region in an elderly patient, which was successfully removed surgically.

This study found that N-acetyl cysteine and metformin had equal effects on clinical outcomes in anovulatory infertile women with PCOS, but NAC was better tolerated with fewer side effects.

This narrative review reports preliminary evidence suggesting that an integrative homeopathic approach, combining constitutional treatment with topical mother tinctures, may aid in healing and reducing inflammatory acne lesions, though larger trials are needed to confirm these effects.

This study found that novel androgen antagonists incorporating a carborane moiety showed anti-androgenic activity comparable to flutamide in a laboratory setting.

This review suggests that skin may largely protect itself from CYP-generated reactive metabolites due to higher conjugating enzyme activities, while highlighting limitations in modeling human skin metabolism experimentally.

This review investigates molecular mechanisms behind PCOS pathogenesis and discusses potential therapies, but reports no new clinical results.

This study found that targeting CISD1 with the compound NL-1 reduced mitochondrial dysfunction and reactive oxygen species accumulation, protecting against cisplatin-induced hearing loss in cell models and mice, without affecting cisplatin's cancer-fighting effectiveness.

This study found that mice lacking the type 3 IP(3) receptor in their hair follicles experienced repetitive hair loss and regrowth, indicating disrupted hair-cycle regulation potentially linked to specific signaling pathways.

2h-ICPR can help screen for insulin antibodies in type 2 diabetes patients.

This study reviews current evidence on the role of ILC3s in the skin, highlighting their potential involvement in responding to microbiome changes such as those associated with acne and suggesting gaps in understanding their mechanisms.

The study found that IPI-926 was well tolerated up to 160 mg once daily for 28-day cycles and showed activity as a single-agent treatment in Hedgehog pathway inhibitor-naïve patients with basal cell carcinoma.

This study reported the development of a workflow that combines SIMS and X-ray elemental mapping techniques for multimodal imaging at the single cell level, successfully applied to visualize elements, metals, and lipids in porcine skin without loss or delocalization.

This study suggests that a biomaterial-based approach using microneedles and ion solutions to deliver SiO3 2− ions may disrupt inflammatory cycles and improve outcomes in inflammatory dilated cardiomyopathy (iDCM).

This study found that CI-1033 caused skin lesions in rats that resemble effects seen in humans receiving EGF receptor inhibitors, suggesting this animal model can help explore the mechanisms behind this cutaneous toxicity.

This paper presents a new device for navigational surgery utilizing the fluorescent properties of Indocyanine Green, offering enhanced intra-operative imaging capabilities by identifying tissues with an infrared CMOS camera.

ICL is a condition with low CD4+ T cells like AIDS but not caused by HIV, and normal CD4+ T cell counts may vary between men and women.

This study suggests that icariin promotes hair follicle growth in mice by enhancing IGF-1 expression in dermal papilla cells.

This study found that ICAM-1 expression in murine skin is developmentally regulated and crucial for skin and hair follicle remodeling beyond its recognized role in immune responses.

This study found that a hydrogel containing icariin enhanced wound healing and hair-follicle regeneration in vivo by promoting M2 macrophage polarization and modulating the BMP pathway, with treated skin defects showing improved recovery and new hair follicle development compared to untreated defects.

This study suggests that Isaria cicadae Miquel rice fermentation extract may enhance regenerative wound healing of hair follicles in mouse skin through the Hippo pathway mechanism.

This article describes a method using the CUBIC protocol to clarify and visualize molecular and cellular interactions in mouse skin biopsies at single cell resolution, but does not provide new biological findings.

This study found that in Arabidopsis, the MYB30-EIN3 module plays a role in adapting root hair development to phosphate deficiency, potentially enhancing phosphate uptake from soil.

In in-vitro experiments, this study found that poncirin showed higher inhibitory activity against JAK3 than tofacitinib, suggesting potential for alopecia areata treatment.

This study found that GLI1 RNA CISH was highly sensitive and specific for distinguishing basal cell carcinoma from nonfollicular epithelial neoplasms but not from most benign follicular tumors.

This study investigated autophagy activator ICP5249 and found it promotes hair growth by enhancing cell proliferation and autophagy-related markers in human dermal papilla cells and hair follicles, with AMPKα playing a regulatory role, suggesting its potential as a hair growth ingredient.

In this study, deleting the Igf1 receptor in specific skin cells of mice affected hair follicle cycling but not overall skin health, suggesting Igf1r's role in hair cycle regulation through Bmp-4 activation.

This study found that upregulation of NFIC may enhance proliferation and osteogenic/cementogenic differentiation in rat dental follicle cells.

CaBP1 and CaBP2 are necessary for proper hearing and neurotransmission in the ear's inner hair cells.

CaBP1 and CaBP2 are necessary for proper hearing and neurotransmission in the ear's inner hair cells.