42 citations
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September 2007 in “The Journal of Clinical Endocrinology and Metabolism” This study found that women with PCOS who have an exaggerated 17-hydroxyprogesterone response to buserelin exhibit more severe hyperandrogenemia, increased insulin secretion, and reduced insulin sensitivity.
7 citations
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March 2018 in “Psychiatry and Clinical Psychopharmacology” This article presents five cases of valproate-induced hyperammonemic encephalopathy in psychiatric patients treated at the authors' clinic and discusses existing literature on this side effect.
17 citations
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September 2000 in “Journal of dermatology” This case report describes a rare instance where a child with nonketotic hyperglycinemia developed an acrodermatitis enteropathica-like eruption, likely due to combined zinc and branched chain amino acid deficiencies.
September 2024 in “Health of Man” This study reports that hyperuricemia, the second most common metabolic disease after diabetes, is linked to numerous health issues, especially in males, and recommends lifestyle modifications as an effective management strategy, highlighting the lack of consensus on uric acid thresholds necessitating drug therapy.
1 citations
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September 2022 in “Canadian Journal of Ophthalmology” This study presents cases of paraproteinemic keratopathy associated with multiple myeloma and MGUS, highlighting varied treatment responses and the need for long-term follow-up to better understand disease progression and management.
96 citations
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February 2007 in “The Journal of Clinical Endocrinology & Metabolism” This review discusses the high prevalence of androgen excess and PCOS in women with type 1 diabetes but reports no new clinical findings; the authors highlight the underdiagnosis of hyperandrogenism in these patients.
May 2023 in “Problems of Endocrinology” This study observed that "physiological" hyperandrogenism due to elevated total testosterone was associated with a 23.5% incidence of arterial hypertension, unlike hyperandrogenism due to elevated DHT levels.
August 2026 in “Genetics and Molecular Research” This study found a significant association between prolactin levels and polycystic ovary syndrome (PCOS), recommending precise investigation of prolactin levels in PCOS patients to identify causes of hyperprolactinemia.
179 citations
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May 1982 in “The Journal of clinical investigation/The journal of clinical investigation” This study found that plasma 3 alpha-diol glucuronide was markedly elevated in women with idiopathic hirsutism, suggesting it may be a marker of peripheral androgen action.
This study found that abnormal carbohydrate metabolism linked to increased serum fasting insulin levels is associated with 20% of women with polycystic ovary syndrome, and these women exhibit more symptoms compared to those with normal insulin levels.
November 2022 in “Journal of the Endocrine Society” This case report describes a patient with ectopic Cushing's syndrome who experienced fatal complications from COVID-19, highlighting the challenges in managing such patients due to immune response alterations from endogenous hypercortisolemia.
25 citations
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September 2015 in “Clinical Endocrinology” This study found that diagnosing nonclassic congenital adrenal hyperplasia in women based solely on serum 17OHP measurements can lead to false positives, suggesting the need for urinary steroid profiles and genetic testing for confirmation.
2 citations
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June 2020 in “AIDS” This case study describes a severe instance of iatrogenic Cushing's syndrome induced by gamma-hydroxybutyric acid, exacerbated by combined use of betamethasone and anabolic steroids, in an HIV-positive patient on cobicistat-containing therapy.
2 citations
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September 2002 in “Journal of Endocrinological Investigation” The GH-IGF-I axis is likely involved in the hormonal imbalances seen in non-obese women with functional hyperandrogenism.
October 2025 in “Journal of the Endocrine Society” In this case report, the coexistence of hypercalcemia and androgen excess in a postmenopausal woman was linked to primary hyperparathyroidism and a suspected androgen-secreting ovarian tumor, underscoring the need for a comprehensive diagnostic approach to identify overlapping endocrine disorders.
3 citations
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March 2012 in “Actas Dermo-Sifiliográficas” An elderly man with skin amyloidosis and abnormal blood proteins was monitored without finding widespread disease after 18 months.
55 citations
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August 2009 in “Journal of Feline Medicine and Surgery” In this case report, a 14-year-old cat was diagnosed with both hyperaldosteronism and hyperprogesteronism linked to a large adrenal tumor, highlighting the importance for clinicians to consider these concurrent conditions in similar cases.
6 citations
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February 1989 in “PubMed” This study suggests that glycation of hair proteins in diabetic patients may serve as a useful indicator of long-term blood glucose trends and associations with diabetic complications.
January 2023 in “Case Reports in Obstetrics and Gynecology” This case report highlights the need for early diagnosis and treatment of ovarian hyperthecosis to enhance the quality of life and health outcomes for affected patients.
1 citations
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August 2015 in “PubMed” This case study reports an Asian female with congenital adrenal hyperplasia presenting atypically with polymenorrhagia, who showed improvement with oral dexamethasone, despite no change in hirsutism or clitoromegaly.
October 2025 in “Journal of Bahria University Medical and Dental College” In this study, among women with polycystic ovary syndrome, free testosterone was most frequently elevated, highlighting its importance in biochemical assessment and suggesting the need for age-related interpretation of DHEAS levels.
December 2022 in “Archives of Clinical Trials” In this case series study, mild ovarian hyperstimulation syndrome was reported in only one out of 118 PCOS patients receiving highly purified HMG injections for IVF treatment.
8 citations
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August 1969 in “Journal of Nutrition” High protein diets improve wound healing and hair growth in calves, regardless of energy intake.
September 2024 in “The Scientific Issues of Ternopil Volodymyr Hnatiuk National Pedagogical University Series pedagogy” This study reports that hyperuricemia is a widespread metabolic condition linked with several diseases, including gout and cardiovascular disease, and highlights the importance of lifestyle modifications, particularly in males, for managing this condition efficiently.
December 2024 in “AACE Clinical Case Reports” This study highlights a rare case of ovarian hyperthecosis in a 58-year-old postmenopausal woman, presenting with polycythemia and severe hyperandrogenism symptoms, with resolution of symptoms following laparoscopic bilateral oophorectomy.
24 citations
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March 2017 in “Archives of Gynecology and Obstetrics” The study found that women with hyperandrogenic PCOS have higher levels of AKT1 and AKT2 proteins in their cells, which may lead to cell dysfunction.
August 1994 in “Molecular Endocrinology” This study found that AtT-20 pituitary cells with higher cAMP-dependent kinase activity had larger calcium currents and significantly increased beta-endorphin release compared to cells with lower kinase activity.
1 citations
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December 2016 in “Journal of Evolution of Medical and Dental Sciences” This study found significant associations between pruritus and elevated parathormone levels, and xerosis and elevated serum creatinine levels, in chronic kidney disease patients undergoing haemodialysis.
2 citations
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August 2020 in “JCRPE” This case report describes a girl with Denys-Drash syndrome misdiagnosed with hyperandrogenism due to biotin interference in immunoassays, highlighting the need for awareness of laboratory result discrepancies.
1 citations
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October 2023 in “Journal of the Endocrine Society” This case presentation reported worsening hyperglycemia in a diabetic male patient after starting finasteride, suggesting that 5-alpha reductase inhibitors may induce hyperglycemia through insulin resistance and liver disturbances in some individuals.