Profile of Skin Changes and Its Association With Biochemical Parameters in Hemodialysis Patients

    December 2016 in “ Journal of Evolution of Medical and Dental Sciences ”
    Pallavi Bakthavatchalu, Ashwini Padubidri Kombettu, Jayadev Betkerur, P A Kushalappa, Chettipunyam S Chetan
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    Studysummary This study found significant associations between pruritus and elevated parathormone levels, and xerosis and elevated serum creatinine levels, in chronic kidney disease patients undergoing haemodialysis.
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    The study examined 62 patients with chronic kidney disease on hemodialysis to identify skin changes and their association with biochemical parameters. The most common skin manifestations were xerosis (74%), pruritus (42%), and diffuse hyperpigmentation (40%). Hair changes included hair loss (24%) and lustreless hair (9%). The study found significant associations between pruritus and elevated parathormone levels (P value: 0.037), as well as between xerosis and elevated serum creatinine levels (P value: 0.026). These findings highlighted the dermatological impacts of hemodialysis and their biochemical correlations.
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