A Study on Clinical Correlation with Hyperinsulinemia in Polycystic Ovary Syndrome

    April 2013
    Govardhan Meena
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    TLDR High insulin levels are more common and a better predictor of carbohydrate issues in women with PCOS than glucose tolerance tests.
    In a study conducted from June 2011 to June 2012, researchers investigated the correlation between hyperinsulinemia and polycystic ovary syndrome (PCOS), a common endocrine disorder in women of reproductive age. The study found that 20% of PCOS patients had abnormal carbohydrate metabolism due to increased serum fasting insulin levels. Symptoms of PCOS, such as hirsutism, obesity, and menstrual disturbances, were more commonly associated with hyperinsulinemic than normoinsulinemic PCOS women. The study also found that hyperinsulinemia was twice as common as abnormal glucose tolerance, indicating that fasting serum insulin levels are a more sensitive predictor of abnormal carbohydrate metabolism in PCOS women than the oral glucose tolerance test.
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