Hyperaldosteronism and Hyperprogesteronism in a Cat

A 14-year-old female neutered domestic shorthair cat exhibited progressive hair loss, muscle wasting, and hind limb weakness, alongside diabetes mellitus, and was diagnosed with primary hyperaldosteronism and hyperprogesteronism due to an adrenal tumor. This case was significant as it was only the second reported instance of these concurrent conditions in cats. Clinical signs included systemic hypertension, hypokalaemia, and metabolic alkalosis, indicative of hyperaldosteronism, and a pot-bellied appearance and skin fragility, suggestive of hyperprogesteronism. Despite treatment, the cat was euthanized 8 weeks later. The study underscored the importance of considering concurrent adrenal disorders in cats with adrenal tumors for accurate diagnosis and treatment.