TLDR Trilostane helped a cat with a hormone issue but the cat later died from a kidney infection.
This report documented the use of trilostane, a steroid synthesis inhibitor, to treat a domestic shorthaired cat with pituitary-dependent hyperadrenocorticism. Trilostane alleviated the severity of clinical signs and was well tolerated. However, the cat later died of renal failure due to a secondary fungal infection of the urinary tract.
10 citations
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February 2007 in “Clinical techniques in small animal practice” Dogs with sex hormone imbalances may not drink or pee a lot but often lose hair on their body and can have reproductive system issues.
116 citations
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April 2002 in “American journal of veterinary research” Trilostane effectively and safely treats dogs with pituitary-dependent hyperadrenocorticism, improving symptoms and adrenal gland size.
6 citations
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January 2013 Hyperadrenocorticism in ferrets is linked to neutering and indoor housing, and is best treated with surgery and a deslorelin implant.
20 citations
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September 2006 in “The Veterinary clinics of North America. Small animal practice/Veterinary clinics of North America. Small animal practice” New drugs are improving treatment for hormone-related diseases in small pets.
10 citations
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May 2018 in “Neuropharmacology” Drugs for hormone-related conditions might help treat mental disorders but could have serious side effects.