Clinical Application of Hair Protein Glycation in the Assessment of Blood Glucose Control and Diabetic Neuropathy

February 1989 in “ PubMed ”

S Masuta, Motohiro Sakai, Takahiro Ohara, Naoya Igaki, Tsuneo Nakamichi, Yoshizane MAEDA, F Hata, M Oimomi, Baba S

hair protein glycation furosine glycated lysine fasting plasma glucose hemoglobin A1c motor nerve conduction velocity sensory nerve conduction velocity

TLDR Hair glycation can indicate long-term blood sugar levels and diabetic nerve issues.

The study assessed the glycation of hair protein in diabetic patients by measuring furosine, a derivative of glycated lysine, in 12-cm-long hair samples representing one year of growth. The level of furosine showed a significant correlation with mean fasting plasma glucose (FPG) and hemoglobin A1c levels, suggesting that hair glycation reflects long-term blood glucose levels. Additionally, motor and sensory nerve conduction velocities correlated better with hair furosine levels than with FPG and hemoglobin A1c, indicating that hair glycation could be a valuable indicator of both long-term blood glucose trends and the relationship between diabetic complications and blood glucose.

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research Glycation of Hair Protein in the Assessment of Long-Term Control of Blood Glucose

6 citations , January 1988 in “Japanese Journal of Medicine”

Hair glycation levels can indicate long-term blood sugar control.