35 citations
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January 2011 in “Journal of Biological Chemistry” This study found that overexpression of sPLA2-X in mice was associated with alopecia and hair follicle abnormalities, highlighting its potential role in hair follicle homeostasis.
33 citations
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August 2008 in “American Journal Of Pathology” This study found that K6a expression in mouse sebaceous gland ducts correlates with Hedgehog signaling, suggesting a role in duct fate.
25 citations
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March 2021 in “Australasian Journal of Dermatology” This case study reports a 70-year-old man with treatment-resistant pityriasis rubra pilaris achieving complete clinical remission with ustekinumab, adding to evidence supporting biologic therapy when TNF inhibitors are unsuitable.
21 citations
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July 2022 in “Orphanet journal of rare diseases” This review discusses recent advancements in therapies for ichthyosis, highlighting promising prospects in protein replacement and gene therapy, but it reports no new clinical results.
21 citations
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July 2018 in “International Journal of Molecular Sciences” This review focuses on the role of the transcription factor Foxn1 in skin biology and discusses its potential implications for regenerative medicine, but reports no new clinical results.
20 citations
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June 2021 in “British Journal of Dermatology” This review provides detailed recommendations for managing cutaneous lupus erythematosus in primary and secondary care but reports no new clinical results.
17 citations
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August 2023 in “Frontiers in Pharmacology” This review highlights the potential of Asteraceae plants as antidiabetic agents and their beneficial effects on conditions such as cardiovascular disease and liver cirrhosis, suggesting their use as food and nutraceuticals could help manage diabetes.
11 citations
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January 2023 in “BioMed Research International” This review discusses the use of microbial biosurfactants as a safer alternative to chemical surfactants in cosmetics due to their antibacterial, moisturizing, and low toxicity properties, but it reports no new clinical findings.
10 citations
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December 2018 in “Internal Medicine” This study reports two cases of myasthenia gravis patients with thymoma who exhibited various autoimmune symptoms including alopecia, suggesting a link between thymus-related immune dysregulation and comorbid conditions.
8 citations
,
February 2022 in “Frontiers in Medicine” This article reports a case of Rowell syndrome in a woman with chronic cutaneous lupus erythematosus that appeared to be triggered by COVID-19 infection, suggesting a potential connection.
5 citations
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January 2025 in “BMC Medical Informatics and Decision Making” This review examines the use of computer vision techniques, specifically deep learning architectures and image processing algorithms, for detecting and assessing skin conditions like vitiligo and dermatitis, and highlights the need for disease-specific datasets to improve automated diagnostic tools in dermatology.
2 citations
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December 2023 in “International journal of molecular sciences” This study reviews the complex keratinization process in the epidermis, detailing how various factors regulate keratinocyte differentiation and emphasizing the importance of understanding this process for the pathogenesis of skin disorders like ichthyoses and psoriasis.
1 citations
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January 2018 in “Skin appendage disorders” This review discusses the role of the complement pathway in alopecia areata and reports no new clinical results; the authors suggest that targeting this pathway could offer treatment options.
August 2026 in “BMC Nephrology” In this study, a young Chinese male with a specific mitochondrial mutation was reported to have proteinuria and renal dysfunction, with stable kidney function after treatment over 23 months.
August 2026 in “Cell Biomaterials” D-chiral biomaterial scaffolds enhance tissue and hair regeneration by activating the body's immune system.
February 2026 in “Nature Communications” In this study, researchers created a detailed human skin cell atlas by analyzing over 700,000 cells, finding that disrupted communication among specific immune and stromal cell subsets may play a key role in initiating and sustaining chronic skin inflammation in atopic dermatitis.
February 2026 in “Molecular and Cellular Probes” This systematic review synthesizes evidence from the past 20 years to highlight the potential of exosome-based therapies from stem cells and plants in improving cutaneous repair, skin aging, and challenging dermatological conditions through mechanisms like immunomodulation and collagen remodeling.
November 2025 in “Journal of Clinical Medicine” This narrative review examined the efficacy and safety of topical tretinoin for various dermatological conditions, finding strong support from robust trials for acne and photoaging, while indicating potential benefits for other uses like melasma and alopecia, yet highlighted the need for more standardized, high-quality trials.
October 2024 in “Medicine” In this case report, a 72-year-old female with Cronkhite-Canada syndrome showed significant improvement in symptoms and gastrointestinal polyps after hormone therapy and additional treatment.
July 2024 in “Clinical Case Reports” In this case study, a 25-year-old presented with symptoms of lupus but tested negative for antinuclear antibodies, complicating diagnosis. The researchers emphasize that comprehensive diagnostic approaches, beyond ANA testing, are vital for effectively identifying and treating lupus nephritis to avoid serious outcomes.
July 2024 in “Biomolecular and Health Science Journal” This case report describes a 33-year-old woman with both subacute cutaneous lupus erythematosus and onychomycosis, highlighting the importance of excluding infections and considering the spectrum of alopecia causes in lupus patients.
April 2024 in “Journal of clinical medicine” This review discusses the diverse cutaneous manifestations of lupus erythematosus and emphasizes the importance of differential diagnosis for effective management, but reports no new clinical findings.
November 2021 in “Frontiers in medicine” This case study documents the first reported instance of bullous lichen planus/systemic lupus erythematosus overlap syndrome with initial hair loss, which improved with treatment including glucocorticoids and immunosuppressive drugs.
February 2009 in “Journal of the American Academy of Dermatology” This abstract compiles a list of medical syndromes and conditions related to tongue abnormalities and other systemic features but reports no new research findings.
July 2025 in “Nano Research” This article discusses how designing biomaterials to modulate immune responses has become a promising strategy for enhancing tissue repair and regeneration.
December 2024 in “International Journal of Molecular Sciences” This study provides a comprehensive overview of human umbilical cord mesenchymal stem cell-derived extracellular vesicles (HUCMSC-EVs), suggesting their potential to combat aging and alleviate age-related disorders by rejuvenating multiple organs in animal models and discussing engineering strategies to harness their full anti-aging potential.
May 2024 in “Clinical Cosmetic and Investigational Dermatology” In this study, researchers reviewed the roles of autophagy and mitophagy in hair follicle cycles, exploring their potential links to hair loss and investigating how manipulating these pathways might offer new therapeutic strategies.
48 citations
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May 1991 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that trichohyalin, a protein previously thought to be restricted to hair and tongue, is also present in isolated cells within the granular layer and stratum corneum of normal human epidermis.
July 2023 in “Clinical Cosmetic and Investigational Dermatology” In this case report, a 64-year-old Thai woman with a history of misdiagnosed eczema or folliculitis was ultimately found to have granular parakeratosis of the eccrine ostium, leading to significant symptom improvement once accurately diagnosed and advised to avoid excessive heat and moisture.