New Developments in the Molecular Treatment of Ichthyosis: Review of the Literature

    July 2022 in “ Orphanet journal of rare diseases ”
    M D W Joosten, J M K Clabbers, Natalie Jonca … Antoni Gostyński
    Studysummary This review discusses recent advancements in therapies for ichthyosis, highlighting promising prospects in protein replacement and gene therapy, but it reports no new clinical results.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
    Read the full study on ojrd.biomedcentral.com →
    Discuss this study in the Community →

    Research cited in this study 10

    1. Genetics of Inherited Ichthyoses and Related Diseases Acta Dermato Venereologica · 2020
    2. Management of Congenital Ichthyoses: European Guidelines of Care, Part Two British Journal of Dermatology · 2018
    3. Cellular and Metabolic Basis for the Ichthyotic Phenotype in NIPAL4 (Ichthyin)–Deficient Canines American Journal Of Pathology · 2018
    4. KLK5 and KLK7 Ablation Fully Rescues Lethality of Netherton Syndrome-Like Phenotype PLoS Genetics · 2017
    5. Inherited Ichthyosis: Syndromic Forms Journal of dermatology · 2016
    6. Ichthyosis with Confetti: Clinics, Molecular Genetics and Management Orphanet Journal of Rare Diseases · 2015
    7. The Molecular Basis of Human Keratin Disorders Human Genetics · 2009
    8. Disorders of Keratinization American journal of clinical dermatology · 2004
    9. Ichthyosis American journal of clinical dermatology · 2003
    10. A Novel Connexin 26 Mutation in a Patient Diagnosed with Keratitis–Ichthyosis–Deafness Syndrome ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2002