TLDR Mycophenolic acid effectively improved hair and nail growth in a lupus patient.
This case report describes a 33-year-old female with cutaneous lupus erythematosus (CLE) who suffered from alopecia universalis and onychomycosis. Initial treatments with corticosteroids, antifungal therapy, and methotrexate were ineffective. However, significant improvement in hair and nail growth was achieved after introducing mycophenolic acid. The report underscores the importance of distinguishing CLE-related alopecia from other conditions and highlights mycophenolic acid as an effective third-line treatment for promoting hair and nail regrowth.
January 2022 in “Skin Appendage Disorders” Areata-like lupus can mimic alopecia areata but is a form of cutaneous lupus erythematosus.
39 citations,
October 2018 in “Lupus Science & Medicine” Different types of hair loss in lupus need careful diagnosis for proper treatment.
45 citations,
January 2018 in “International Journal of Dermatology” Nail problems are common in people with alopecia areata, often leading to cosmetic and functional issues, but more research is needed for treatment guidelines.
1 citations,
January 2021 in “Journal of the American Academy of Dermatology” Careful histologic examination is crucial to differentiate types of bullous lesions in cutaneous lupus erythematosus.
30 citations,
September 2005 in “Best Practice & Research Clinical Rheumatology” The document concludes that treating tough skin disease in lupus involves sun protection, steroids, antimalarials, and various other therapies chosen based on individual risks and benefits.
