TLDR Myasthenia gravis can affect both motor and non-motor systems due to immune system issues.
The document discussed the non-motor comorbidities of myasthenia gravis (MG), emphasizing its nature as a systemic immunological disorder affecting various non-motor systems. It highlighted that patients with MG often experienced cognitive dysfunction, mood disorders, sleep disturbances, and other conditions such as alopecia areata, thymoma, taste disorders, cardiac involvement, nephrotic syndrome, and multiorgan autoimmunity. The study underscored the importance of recognizing and managing these non-motor symptoms to provide comprehensive care for MG patients, particularly in thymoma-associated cases.
49 citations,
November 2012 in “Journal of neurology, neurosurgery and psychiatry” Non-motor symptoms in myasthenia gravis are common and need early diagnosis for better management.
26 citations,
June 2018 in “The journal of immunology/The Journal of immunology” AIRE-deficient rats developed severe autoimmune disease similar to APECED, useful for testing treatments.
2 citations,
December 2023 in “Journal of clinical immunology” Ruxolitinib significantly improves multiple autoimmune conditions in APS-1 patients.
January 2024 in “Biomedicines” The review shows that skin symptoms like chronic fungal infections, hair loss, and skin depigmentation are key for early detection and management of APECED.
90 citations,
July 2008 in “Dermatologic therapy” Lichen planopilaris is a chronic, scarring hair loss condition with no definitive cure, requiring accurate diagnosis and treatment to manage symptoms.
31 citations,
March 2018 in “Frontiers in Immunology” The document concludes that anti-dsDNA antibodies are not unique to SLE and their use as indicators is doubtful, highlighting the need for better understanding and classification of the disease.
