research Persistent Sexual and Nonsexual Adverse Effects of Finasteride in Younger Men
Finasteride can cause sexual problems and depression in young men.
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research Dermatological Manifestations of Stress in Normal and Psychiatric Populations
Stress can worsen skin conditions and affect mental health, so doctors should include stress management in skin treatment.
research The Androgen Receptor and Its Use in Biological Assays: Looking Toward Effect-Based Testing and Its Applications
Scientists have developed a new method to detect steroid abuse in athletes using cell-based tests, which could be the future of anti-doping methods.
research Phenolsulphotransferase: Localization in Kidney During Human Embryonic and Fetal Development
The enzyme PST is found in developing human kidneys and helps with detoxification and development.
research The New Paradigm for Androgenetic Alopecia and Plant-Based Folk Remedies: 5α-Reductase Inhibition, Reversal of Secondary Microinflammation, and Improving Insulin Resistance
Plant-based remedies may treat hair loss by reducing inflammation and improving insulin resistance.
research Compilation of a Comprehensive Gene Panel for Systematic Assessment of Genes That Govern an Individual’s Drug Responses
Researchers found that most genes affecting drug responses are not fully covered by commercial SNP chips, suggesting the need for more comprehensive tools to optimize drug selection based on genetics.
research Integrated Chemometric Fingerprints of Antioxidant Activities and HPLC-DAD-CL for Assessing the Quality of the Processed Roots of Polygonum Multiflorum Thunb. (Heshouwu)
The research identified 12 antioxidant compounds in Polygonum multiflorum roots, suggesting these as quality markers for the plant's processed roots.
research Bipolar Disorders and Valproate: Pharmacokinetics, Pharmacodynamics, Therapeutic Effects, and Indications of Valproate: Review of Articles
Valproate is a mood stabilizer for bipolar disorder but has side effects and risks, especially during pregnancy.
research Fatal Toxic Epidermal Necrolysis Associated With Minoxidil
Minoxidil can cause deadly skin reaction; monitor patients closely.
research Selective and Rapid Determination of Tadalafil and Finasteride Using Solid Phase Extraction by High Performance Liquid Chromatography and Tandem Mass Spectrometry
Quick, selective detection of tadalafil and finasteride in human plasma developed.
research Chemical Compatibility and Safety of Imidacloprid/Flumethrin Collar (Seresto) Concomitantly Used with Imidacloprid/Moxidectin (Advocate, Advantage Multi) and Emodepside/Praziquantel (Profender) Spot-on Formulations
Seresto® collar is safe to use with Advocate® and Profender® on dogs and cats.
research Indian Gooseberry (Emblica Officinalis Gaertn.) Pharmacological Properties
Indian Gooseberry has potential for cancer prevention and treatment and promotes hair growth.
research ADT-G as a Promising Biomarker for Peripheral Hyperandrogenism in Adult Female Acne
ADT-G may be a useful indicator of increased androgen levels in women with acne and can be lowered with certain birth control pills.
research Finasteride for Hair Loss: A Review
Finasteride helps hair growth but may cause sexual side effects and depression.
research Glucocorticoid and Sex Hormone Receptors: Clinical Implications and Therapeutic Relevance
Glucocorticoids and sex hormones affect skin health, with potential for targeted treatments to minimize side effects and treat skin conditions.
research Influence of Saw Palmetto and Pygeum Africana Extracts on the Urinary Concentrations of Endogenous Anabolic Steroids: Relevance to Doping Analysis
Taking Saw palmetto and Pygeum africana can change the levels of certain steroids in urine, which could cause confusion in doping tests.
research High-Resolution Mass Spectrometric Investigation of the Phase I and II Metabolites of Finasteride in Pig Plasma, Urine, and Bile
Finasteride metabolites found in pigs match human studies, making pigs a valid model for human drug research.
research Paternal Finasteride Treatment Can Influence the Testicular Transcriptome Profile of Male Offspring—Preliminary Study
Father's finasteride use may affect son's fertility and testicular function.
research Therapeutic Aspects of Onion in Treatment of Cancer and Related Issues: A Review
Onions may help reduce cancer risk and obesity-related issues.
research Novel Type 1 5a-Reductase Inhibitors With Antiproliferative Potential On LNCaP Cells
New compounds may help treat prostate cancer by reducing cell growth.
research Concept of Tinea Capitis
Terbinafine is the most effective treatment for tinea capitis, a scalp infection often confused with other conditions.
research Genome Scan for Signatures of Adaptive Evolution in Wild African Goat (Capra Nubiana)
Wild African goats have genetic adaptations for surviving harsh desert conditions.
research Antiandrogens and Androgen Inhibitors in Dermatologic Treatments
Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.
research Pharmacodynamic Evaluation: Endocrinology
The conclusion is that endocrinology significantly impacts medicine with various common medications used for treatment.
research Finasteride
Finasteride helps hair growth and prostate issues but may cause sexual side effects and increase tumor risk.
research EtG Quantification in Hair and Different Reference Cut-Offs in Relation to Various Pathologies: A Scoping Review
This scoping review explores the use of ethyl glucuronide (EtG) in hair as a marker for alcohol consumption, particularly in individuals with liver and kidney diseases, diabetes, and transplant recipients. It highlights that these conditions can affect EtG levels, leading to potential false positives or negatives. Renal dysfunction can cause high EtG concentrations due to delayed excretion, complicating alcohol consumption interpretation. The review emphasizes the need for careful consideration of these pathologies and calls for further research to refine EtG testing methods and establish accurate cut-off levels. Despite limitations, hair EtG testing can improve alcohol consumption detection, especially in liver disease patients, with varying sensitivity and specificity based on disease severity and cut-off levels.
research Androgens and Androgen Receptor in the Management of Skin Diseases
Understanding how androgens and their receptors work can lead to improved treatments for skin diseases.
research Effects of Vinblastine and Its Metabolites on Nausea and Alopecia Associated Receptors
Vinblastine and its metabolites may cause nausea and hair loss by binding to specific receptors and could lead to better chemotherapy drugs with fewer side effects.
research Sodium Valproate for Painful Peripheral Neuropathy in Diabetic Patients
Sodium valproate is not recommended as a first-line treatment for neuropathy but may be used in resistant cases.
research Topical Finasteride Dose Evaluation for Treatment of Androgenetic Alopecia Using Computer Simulations
Topical finasteride at 0.25% is effective and has fewer side effects than oral finasteride for hair loss.