Experimental and Clinical Pharmacology of Ziziphus Jujuba Mills

    January 2017 in “ Phytotherapy Research
    Javier Rodríguez Villanueva, Laura Salanova Villanueva
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    TLDR Ziziphus jujuba Mills may have health benefits, but more research is needed to confirm its safety and effectiveness.
    The document provides a detailed review of the pharmacological properties and potential health benefits of Ziziphus jujuba Mills, a plant used in traditional medicine. It covers the plant's bioactive compounds, such as polysaccharides, flavonoids, triterpenic acids, and saponins, which contribute to its hepatoprotective, antioxidant, anti-inflammatory, and anticancer activities. The review also discusses the effects of different drying methods on the fruit's compound content, the need for more high-quality clinical trials to establish the safety and efficacy of Z. jujuba-based treatments, and the lack of toxicity studies. It highlights the plant's potential for treating various disorders, including dyslipidemia, hair growth promotion, and menopausal symptoms, and emphasizes the need for standardized extracts and more rigorous clinical trials to confirm the non-clinical observations. The document also notes the challenges in integrating traditional Chinese medicine with modern medical systems and the importance of regulatory agencies in increasing consumer confidence in botanical products. However, specific data on the number of people involved in clinical studies, if any, were not provided.
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