Recent Formulation Advances of Mangiferin

October 2022 in “ Revista Brasileira de Farmacognosia ”

Sara Barakat, Maha Nasr, Rania F. Ahmed, Sabry S. Badawy, Nahed D. Mortada

mangiferin polyphenol lipidic nanoparticles vesicular nanoparticles polymeric nanoparticles inorganic nanoparticles protein nanoparticles nutraceutical mango tree extract

Studysummary This review discusses the pharmacological actions of mangiferin and the potential of delivery carriers to overcome its limitations, but reports no new clinical results.

Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer

The document reviewed the pharmacological actions of mangiferin, a polyphenol from the mango tree, highlighting its potential in treating various diseases due to its favorable pharmacological properties. However, mangiferin's efficacy was limited by poor aqueous solubility and low bioavailability. The review discussed how different delivery carriers, including lipidic, vesicular, polymeric, inorganic, and protein nanoparticles, as well as complexes, could address these challenges. These advancements in formulation were shown to enhance the bioavailability and therapeutic effects of mangiferin, improving its potential as a nutraceutical.

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