TLDR Improved delivery methods can enhance mangiferin's effectiveness as a health supplement.
The document reviewed the pharmacological actions of mangiferin, a polyphenol from the mango tree, highlighting its potential in treating various diseases due to its favorable pharmacological properties. However, mangiferin's efficacy was limited by poor aqueous solubility and low bioavailability. The review discussed how different delivery carriers, including lipidic, vesicular, polymeric, inorganic, and protein nanoparticles, as well as complexes, could address these challenges. These advancements in formulation were shown to enhance the bioavailability and therapeutic effects of mangiferin, improving its potential as a nutraceutical.
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