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Finasteride breakdown products found in bile and urine, helps understand drug safety and effectiveness.

Women with hair loss have higher androgen levels, while men with early balding have altered androgen ratios.

People with hair loss may have different levels of certain hormones due to changes in hormone processing.

Drug metabolism affects how long a drug works, its interactions, activation, and toxicity, and is influenced by genetics, diet, illness, and other drugs.

Too much androgen can cause hair loss; finasteride may help.

Finasteride affects UGT1A4 enzyme, but not enough to cause issues when combined with other drugs.

Androgens, like DHT, affect hair growth and treatments like finasteride may help.

Cabergoline is more effective and has fewer side effects than bromocriptine for treating women with hyperprolactinemic amenorrhea.

Higher doses of oestradiol implants improve bone density in postmenopausal women.

Long-term use of oral contraceptives, especially starting before age 20, may increase the risk of early-onset breast cancer.

Managing metabolic syndrome needs both lifestyle changes and medical treatments.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

Anticancer drugs are increasingly found in surface waters, and their long-term environmental effects are not well understood, requiring better testing methods.

Human skin makes sexual hormones that affect hair growth, skin health, and healing; too much can cause acne and hair loss, while treatments can manage these conditions.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Sebocytes play a key role in controlling androgen levels in human skin.

Epirubicin is as effective as doxorubicin for cancer treatment with less heart damage, but doesn't work on doxorubicin-resistant cancers.

SAHA syndrome is a condition in women involving skin and hair issues, often related to hormonal imbalances, and is treated based on the underlying cause.

PCOS affects women's health by increasing the risk of diabetes, heart disease, and reproductive issues.

Genetics and hormones cause hair loss; finasteride treats it safely.

Androstanediol glucuronide is a reliable marker for hirsutism in women.

Human enzymes can detoxify harmful substances but might also increase their cancer risk.

Valproic Acid could potentially be used to treat immune-related conditions due to its ability to modify immune cell functions.

Too much AKR1C3 enzyme causes resistance to finasteride by increasing testosterone.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

The study developed a tool to predict how gut microbes process foods and drugs, showing that similar compounds often share metabolic pathways and effects.

Ziziphus jujuba Mills may have health benefits, but more research is needed to confirm its safety and effectiveness.

New resveratrol-related compounds show promise for treating various health issues but need more research for clinical use.

Cheonggukjang may help prevent and manage various diseases and improve overall health, but its odor and safety concerns need addressing.