Integrated Chemometric Fingerprints of Antioxidant Activities and HPLC-DAD-CL for Assessing the Quality of the Processed Roots of Polygonum Multiflorum Thunb. (Heshouwu)

    April 2016 in “ Chinese Medicine
    Hai Fang Chen, You Hua Chen, Chunhua Liu, Lu Wang, Xialin Chen, Yu B, Jin Qi
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    TLDR The research identified 12 antioxidant compounds in Polygonum multiflorum roots, suggesting these as quality markers for the plant's processed roots.
    In the 2016 study, Chen et al. evaluated the quality of processed roots of Polygonum multiflorum Thunb. (HSW) by integrating chemometric fingerprints of antioxidant activities with high-performance liquid chromatography-diode array detection-chemiluminescence (HPLC-DAD-CL). The research aimed to identify potential anti-aging constituents in 14 batches of HSW from various habitats. The study found that the batches were generally similar, forming two clusters, and identified 12 active compounds with antioxidant activity, with six significantly influencing sample differences. Stilbene glucosides and other compounds like gallic acid and emodin were highlighted for their ROS scavenging abilities. The study did not mention the number of samples tested for antioxidant activity but proposed specific compounds as chemical markers for quality control of processed HSW, emphasizing the need for standardized processing technology.
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