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This study found that 'smart' peptide hydrogels improved wound healing in a rat model of partial thickness burns, achieving greater wound closure and faster debridement compared to a standard treatment.

This study reported that a newly developed hydrogel composed of recombinant type I collagen and chitosan, incorporating a metal–polyphenol structure, demonstrated strong mechanical and healing properties, effectively promoting wound healing in a full-thickness skin defect model.

In this study, composite dressings made from SP nanofibers, Megel hydrogel, and cotton nonwoven significantly accelerated wound healing in diabetic mice, achieving ∼98% closure within 18 days, while enhancing tissue regeneration and reducing inflammation.

In this study, the researchers developed a living microecological hydrogel containing Chlorella and Bacillus subtilis that showed potential in promoting the healing of infected diabetic wounds by providing continuous oxygen delivery and anti-infective properties.

This study found that a microenvironment-responsive ATAN-Met hydrogel system improved infective diabetic wound healing by enhancing re-epithelialization, neurovascular and hair follicle regeneration, and exhibited antibacterial and immunoregulatory effects, activated beneficial pathways, and responded to glucose/ROS for drug release.

This study found that energy emitted by a hydrocolloid-based wound dressing fragment can penetrate glass and delay the evaporation of a Potassium Ferricyanide solution around a human hair follicle in vitro.

This study found that AGO@HPC nanocomposite films demonstrated enhanced mechanical, anti-ultraviolet, and antibacterial properties, suggesting potential for use in antibacterial packaging and wound-dressing applications.

This study found that the pH-sensitive hydrogel HECHA13, containing isoliquiritigenin, effectively inhibited the growth of Propionibacterium acnes and showed promise for transdermal delivery in acne treatment.

This review discusses photothermal agent hybrids in hydrogels for antibacterial action, angiogenesis, and osteogenesis in tissue engineering, but reports no new experimental findings.

This study found that incorporating cell-adhesive ligands into 3D peptide hydrogels supports the survival and osteogenic differentiation of human amniotic mesenchymal stem cells.

In this study, HYDRO DELUXE BIO was reported to show promise for scalp mesotherapy by enhancing angiogenesis and reducing inflammation in an in vitro model.

This study found that a novel hydrogel scaffold, cGEL, significantly increased melanin production and melanotic gene expression in human melanocytes compared to other graft materials, suggesting its potential as a superior carrier for skin grafting.

In this study, hydrophilic EG7 PTK-UR foams promoted better wound healing and tissue integration in a porcine model compared to more hydrophobic PTK-UR variants and a polyester-based alternative, while matching a collagen-based standard.

This study reported that the use of composite RGDmix hydrogel improved the survival and proliferation of human amniotic mesenchymal stem cells and increased growth factor expression, enhancing wound healing through the RGDSP/integrin αv/PI3K/AKT signaling pathway.

This review discusses the potential of peptide-based hydrogels as biomaterials for treating chronic wounds and reports no new clinical findings.

This study found that an optimized hydrogel combined with human umbilical cord-mesenchymal stem cells accelerated wound healing in diabetic mice by improving cell adhesion and reducing inflammation.

The hydrogel is safe, reduces oxidation, and helps heal wounds effectively.

This study demonstrated that a 3D bioprinting technique using a gelatin/alginate hydrogel scaffold can regenerate entire hair follicles in mice, offering potential advancements in hair loss treatment.

This review explores how recombinant protein hydrogels, employing molecular engineering and crosslinking strategies, offer advanced applications in regenerative medicine by mimicking extracellular matrix dynamics and providing enhanced mechanical, environmental, and biological properties.

This study found that microencapsulated dermal papilla cells in hyaluronic acid/collagen hydrogel retained their ability to initiate hair follicle regeneration, suggesting potential for alopecia treatment.

This manuscript explores the development and future potential of injectable biomimetic gels in biomedical applications, highlighting their promise in wound healing and tissue regeneration, while also acknowledging challenges like mechanical durability and scalable production still persist.

This study found that a newly developed injectable hydrogel combined with human umbilical cord-mesenchymal stem cells significantly accelerated wound healing and reduced inflammation in full-thickness cutaneous wounds.

This study found that biodegradable hydrogels loaded with various growth factors significantly enhanced hair follicle growth and blood vessel formation in mice, demonstrating a positive effect on their hair growth cycle.

In this study, researchers used a new method with platelet-rich plasma-loaded microcarriers to enhance dermal papilla cell activity and hair follicle regeneration, achieving significant hair and vessel growth in a mouse model compared to control groups.

This study suggests that human placenta hydrolysate reduces CFA-induced inflammatory pain in mice by inhibiting pro-inflammatory cytokines and protecting peripheral nerves.

This review reports that sodium alginate-based hydrogels show promise in biomedical applications due to their biocompatibility and versatility, but challenges such as mechanical strength and stability remain, highlighting the need for continued research to facilitate their clinical transition.

This review discussed the potential of multifunctional photoresponsive hydrogels for wound regeneration, highlighting various types prepared with diverse photosensitizers and photothermal/photodynamic agents, and explored their role in modulating bacterial microenvironments to inhibit infection and promote healing.

This study demonstrates that an injectable gelatin-based hydrogel incorporating zirconium and quercetin promotes diabetic wound healing in vivo by enhancing angiogenesis, collagen deposition, and hair follicle regeneration while providing antibacterial and oxidative stress protection without detectable cytotoxicity.

In this study, the researchers developed a biomimetic multilayer composite scaffold combining a decellularized amniotic membrane, fibroblast-laden collagen gel, and epidermal stem cells, which healed full-thickness skin wounds more quickly and effectively by regenerating hair follicles without scarring compared to Moropicin ointment.