1 citations
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July 2019 in “Journal of the Korean Society of Food Science and Nutrition” This study found that platycodon ethanol extract showed potential as a natural ingredient for hair loss prevention by increasing radical scavenging ability, inhibiting inflammation, and affecting DHT generation in laboratory experiments.
1 citations
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April 2023 in “International Journal of Molecular Sciences” This study found that Botryococcus terribilis ethanol extract significantly reduced inflammation markers in LPS-stimulated RAW264 cells, potentially via Axl inhibition and alteration of immune-related gene expression.
10 citations
,
January 2022 in “Journal of Research in Pharmacy” In this experimental study on Wistar albino rats, Cotinus coggygria leaf extract demonstrated potential as a treatment for burn-induced skin damage by reducing cytokine levels and promoting tissue healing.
8 citations
,
August 2018 in “Drug testing and analysis” This study observed that ethyl glucuronide (EtG) concentrations in hair decreased significantly during an abstinent period, suggesting possible wash-out effects or other factors affecting EtG levels.
36 citations
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June 2012 in “Alcoholism Clinical and Experimental Research” This study found that patients with decreased kidney function had significantly higher hair levels of ethyl glucuronide compared to healthy individuals, suggesting these results should be cautiously interpreted.
June 2024 in “Current Developments in Nutrition” In this study, KeraGLO, a nutritional supplement with hydrolyzed keratin, was shown to significantly improve skin wrinkle depth, smoothness, moisture, firmness, and hair health in healthy adult females over a 90-day period at both 500mg and 1000mg doses compared to baseline.
5 citations
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August 2014 in “Pharmaceutical Development and Technology” In this study, the researchers reported that while both propylene glycol and sodium lauryl sulfate enhanced finasteride's skin deposition, ethanol was the only effective enhancer of finasteride's permeation through the skin.
July 2012 in “Ubaya Repository (University of Surabaya)” This study found that hair growth gel and tonic containing red grape seed extract were physically and chemically unstable under high temperature and humidity conditions over 30 days.
7 citations
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July 2019 in “International Journal of Molecular Sciences” This study found that PGA-4HGF nanoparticles enhanced hair growth in mice more effectively than 4HGF alone by increasing anagen phase duration and dermal papilla cell proliferation.
May 2026 in “Scientific Reports” This study found that kukui nut oil (AMS oil) promotes hair growth in human hair follicle cultures by increasing PGF2α levels and activating Nrf2 signaling, and a human trial confirmed its efficacy in enhancing eyelash growth.
This study found that isolated human scalp hair follicles express PGE2 genes and EP2 protein, suggesting PGE2 may play a crucial role in regulating hair growth.
May 2025 in “Journal of Experimental Pharmacology” This study found that Allium ascalonicum L. extract may improve insulin resistance by increasing insulin tolerance test values and lowering blood glucose levels, though more research is needed to understand its effects on metabolic disorders.
34 citations
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April 2007 in “Neuroscience” In this study, finasteride altered acute ethanol withdrawal severity differently in male and female mice, highlighting sex differences in sensitivity to changes in neurosteroid levels.
55 citations
,
June 2009 in “Journal of Pharmaceutical Sciences” This study found that ethanol-containing formulations significantly increased minoxidil retention in the stratum corneum and appendages initially, while a propylene glycol-rich formulation enhanced deeper skin penetration over time.
This study focused on developing a nanoemulsion-based gel for delivering minoxidil, aiming to enhance its contact time with the scalp and potentially improve skin absorption compared to conventional topical solutions.
39 citations
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April 2010 in “International Journal of Pharmaceutics” This study found that using monoolein cubic phase nanoparticles with an entrapped hydroxypropyl β-cyclodextrin/minoxidil complex increased minoxidil skin permeation, but minoxidil retention in the skin was higher with a traditional solution.
43 citations
,
July 2013 in “Pharmacological reviews” This article reviews the pharmacology of bimatoprost and prostamide F2α, highlighting bimatoprost's therapeutic applications in glaucoma, hair growth, and potential fat reduction, without reporting new experimental results.
3 citations
,
October 2014 in “Pharmaceutical Development and Technology” This study found that an optimized microemulsion for minoxidil with high solubility, permeation flux, and skin deposition can be achieved with specific low and high levels of certain surfactants and co-solvents.
32 citations
,
November 2020 in “Nanomaterials” This study found that excipients significantly influence the effectiveness of curcumin nanocrystals in dermal applications, enhancing or hindering hair follicle targeting and passive diffusion based on their selection.
75 citations
,
November 1965 in “Textile research journal” This study found that papain/bisulfite disintegrates human hair cuticles by dissolving the endocuticle, potentially accelerated by ethanol's removal of cell membrane material.
61 citations
,
September 2010 in “Fitoterapia” This study found that the EtOAc extract of Tridax procumbens aerial parts significantly inhibited rat paw edema and COX enzyme activity, suggesting its potential anti-inflammatory properties.
37 citations
,
October 2009 in “Dermatology” This study suggests that the action of minoxidil in stimulating hair growth likely occurs at the follicular dermal papilla, though it does not induce new follicle formation.
12 citations
,
January 2010 in “European Journal of Dermatology” In this study, an ethanol extract of Crinum asiaticum was observed to significantly increase hair-fiber lengths and promote hair growth in rat vibrissa follicles and C57BL/6 mice.
8 citations
,
June 2021 in “Frontiers in Bioengineering and Biotechnology” This study investigated the effects of the 60% alcohol extract from Alnus sibirica and its active compound, oregonin, on hair health, observing anti-oxidative and anti-apoptotic benefits in human hair dermal papilla cells exposed to oxidative stress, suggesting potential as natural materials for hair loss prevention.
4 citations
,
January 1994 in “Yakugaku zasshi” In this study, EPC-K, a compound with antioxidant and moisturizing effects, was found to decompose significantly under certain conditions, impacting its stability in quasi drug hair-growing products.
1 citations
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July 2005 in “Informa Healthcare eBooks” Hair follicles could be used for targeted drug delivery, with liposomal systems showing promise for this method.
January 2018 in “International journal for pharmaceutical research scholars” In this study, topical application of tonic preparations containing 5% ethanol extract of Phyllanthus niruri to shaved mice showed potential as a hair growth enhancer, as indicated by observations of increased hair length and weight over a 21-day period.
March 2026 in “International Journal of Molecular Sciences” This study found that Grateloupia angusta extract improved wound healing by promoting matrix production and pro-angiogenic activity in cell cultures and enhanced early wound repair in a mouse skin incision model.
October 2022 in “Asian journal of healthy and science” This study found that a 20% concentration of mother-in-law's tongue leaf extract promoted hair growth in male rabbits, with effectiveness comparable to a positive control.
7 citations
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February 2019 in “Journal of Molecular Liquids” This study assessed minoxidil solubility in propylene glycol and water mixtures, comparing cosolvency models and examining thermodynamic properties, without reporting new clinical results.