The Effects of the Ethanol Extract of Allium Ascalonicum L. in High-Fat High-Fructose Induced Insulin Resistance in Swiss-Webster Male Mice

    May 2025 in “ Journal of Experimental Pharmacology ”
    Rani Yulifah Elkanawati, Sri Adi Sumiwi, Jutti Levita
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    Studysummary This study found that Allium ascalonicum L. extract may improve insulin resistance by increasing insulin tolerance test values and lowering blood glucose levels, though more research is needed to understand its effects on metabolic disorders. Our plain-language summary of this paper — not a Tressless recommendation.
    The study investigates the effects of Allium ascalonicum L. extract on insulin resistance (IR) in Swiss-Webster male mice induced with a high-fat-high-fructose diet. The findings suggest that the extract may improve IR conditions, as evidenced by an increase in insulin tolerance test (ITT) values and a reduction in blood glucose levels. Despite these promising results, further research is necessary to confirm the extract's potential in alleviating metabolic disorders.
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