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This study found that testosterone-enanthate increased red blood cell production and altered iron homeostasis in older hypogonadal men without being affected by finasteride, indicating these effects do not require type II 5α-reductase enzyme activity.

Testosterone needs to be converted to DHT to reduce stress response in male rats.

In this animal study, administering testosterone alongside a 5α-reductase inhibitor counteracted testosterone's effects on prostate enlargement while preserving its beneficial effects on muscle and bone.

This guideline provides recommendations for prescribing systemic testosterone to women with hypoactive sexual desire disorder, emphasizing safe dosing, monitoring, and the need for informed consent despite regulatory challenges.

This study found that testosterone treatment in older hypogonadal men caused minor improvements in depressive symptoms and visuospatial memory, but overall, major cognitive benefits were not observed.

In this study, male-pattern baldness was strongly associated with a higher risk of keratinocyte cancers, particularly squamous cell carcinoma and melanoma, likely due to increased sun exposure on the scalp rather than androgen levels.

In this study on male rats, parachlorophenylalanine treatment induced hypersexual behavior and hair loss linked to increased social interaction but had no effect on brain serotonin when testosterone was used instead.

This case report describes a functional adrenocortical oncocytoma that co-secreted testosterone and cortisol.

This study found that MENT is 10 times more potent than testosterone in suppressing gonadotropins and contributing to anabolism in monkeys, with a potentially wider therapeutic index for human androgen replacement and male contraception.

This study observed that direct exposure to androgens in Western clawed frogs differentially affects thyroid receptor and deiodinase gene expression in male and female tissues, offering insight into sex-specific metabolic pathway activation.

This study concluded that both vaginal TEST and Estring may be effective for treating vaginal dryness in breast cancer patients on aromatase inhibitors, with adverse events being rare and manageable.

This study found that serum testosterone levels significantly increased during major head and neck surgeries in maxillofacial surgeons, influenced by factors like tumor size and procedural complexity.

A postmenopausal woman's masculine symptoms improved after surgery for a hormone-producing ovarian tumor.

This study found that acne prevalence in late pubertal boys was 85%, compared to 15% in girls, with higher DHT levels noted in acne-affected adolescents compared to those without.

This study found that Zhuangyao Jianshen pill significantly improved prostate health in testosterone-induced benign prostatic hyperplasia in castrated rats by modulating sex hormones and reducing inflammation and oxidative stress.

In this animal study, AGO (agomelatine) effectively alleviated testosterone-induced benign prostatic hyperplasia in rats by reducing oxidative stress and inflammation, indicating its potential as a therapeutic option for managing BPH through specific signaling pathways.

In this case study, a 12-year-old boy with Cushing's Disease experienced a complex diagnostic journey; ultimately, a left-side ACTH-secreting microadenoma was identified and treated with gamma knife therapy, normalizing hypercortisolism but resulting in growth hormone deficiency.

In this case series, researchers reported an unexpectedly rapid and positive response to a topical, hydrogel-based botanical treatment for androgenetic alopecia in both male and female volunteers, achieving significant improvement in hair loss within 90 days instead of the planned 270 days.

In this pilot randomized clinical trial, TRT combined with finasteride increased lean mass, muscle size, and bone mineral density without prostate enlargement in men with spinal cord injury, suggesting potential benefits for body composition and musculoskeletal health.

In this retrospective chart review, researchers observed that estrogen monotherapy effectively suppressed testosterone levels below 50ng/dL in all transfeminine patients studied, particularly those using injectable formulations, though the small sample size and ongoing data collection limit these findings.

In this retrospective study, among transfeminine patients aged 19-81 receiving gender-affirming estrogen therapy, 100% achieved testosterone suppression without anti-androgens when serum estradiol exceeded 100pg/mL, predominantly using injectable estrogen.

This study found that untargeted hair metabolomics analysis detected significantly altered endogenous biomolecules, potentially serving as biomarkers for identifying oxidative cosmetic hair treatments like bleaching.

This study found that a phyto-caffeine-containing shampoo was more effective than a control shampoo in reducing hair loss and improving hair strength in women with androgenetic alopecia over a 6-month period.

This study reports that treating a feline with progressive pruritus, alopecia, and FIV infection with imidacloprid and moxidectin resulted in remission of clinical signs and elimination of Demodex cati mites, as confirmed by parasitological examination and genetic sequencing.

This review discusses the use of hair analysis for examining stress and reproduction hormone levels in wildlife and highlights the need for more comprehensive physiological validations across species.

This study found that the Transdermal Delivery System efficiently delivers testosterone systemically and showed bioequivalent hormone concentrations to a known topical gel in healthy males.

This study found that recombinant hepatitis B vaccine may increase the risk of alopecia areata onset in older predisposed mice but larger trials suggest this effect might lie within normal variation.

This study examined the clinicopathologic features of mesothelioma of the tunica vaginalis testis in 14 patients, finding that the disease mostly presented as epithelioid type, with a propensity for high-grade tumors, and BAP1 and MTAP loss was uncommon.

This study found that cortisol concentrations were significantly higher in hair samples with follicles compared to those without, suggesting potential confounding in stress assessments using different hair sampling methods.