Adolescent Acne: Association to Sex, Puberty, Testosterone and Dihydrotestosterone

March 2025 in “ Endocrine Connections ”

Nanna E. Jakobsen, Jørgen Holm Petersen, Lise Aksglæde, Casper P. Hagen, Alexander S. Busch, Trine Holm Johannsen, Hanne Frederiksen, Anders Juul, Stine Agergaard Holmboe

acne testosterone dihydrotestosterone androgens puberty DHT

Studysummary This study found that acne prevalence in late pubertal boys was 85%, compared to 15% in girls, with higher DHT levels noted in acne-affected adolescents compared to those without.

Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer

View this study on ec.bioscientifica.com →

Discuss this study in the Community →

Research cited in this study

2 / 2 results

research Efficacy, Tolerability, and Safety of Montelukast Versus Finasteride for the Treatment of Moderate Acne in Women: A Prospective, Randomized, Single-Blinded, Active-Controlled Trial

2 citations , October 2021 in “Journal of Cosmetic Dermatology”

In this randomized trial, the researchers observed that both montelukast and finasteride effectively reduced acne severity and lesion count in women with moderate acne, but finasteride showed greater efficacy. Both medications had transient, non-serious side effects, indicating satisfactory tolerability and safety.

research Sex Hormones and Acne: The Role of the Skin as an Endocrine Organ

76 citations , October 2016 in “Clinics in dermatology”

This review discusses the hormonal and genetic factors influencing acne development, emphasizing the role of androgens and insulin signaling but reports no new clinical results.