Efficacy, Tolerability, and Safety of Montelukast Versus Finasteride for the Treatment of Moderate Acne in Women: A Prospective, Randomized, Single-Blinded, Active-Controlled Trial

    October 2021 in “ Journal of Cosmetic Dermatology ”
    Ghasem Rahmatpour Rokni, Farzaneh Mohammadnezhad, Majid Saeedi … Mohamad Goldust
    Studysummary In this randomized trial, the researchers observed that both montelukast and finasteride effectively reduced acne severity and lesion count in women with moderate acne, but finasteride showed greater efficacy. Both medications had transient, non-serious side effects, indicating satisfactory tolerability and safety.
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    Research cited in this study 7

    1. Acne Vulgaris: New Evidence in Pathogenesis and Future Modalities of Treatment Journal of Dermatological Treatment · 2021
    2. Finasteride and Androgenic Alopecia: From Therapeutic Options to Medical Implications Journal of Dermatological Treatment · 2019
    3. Anti-Acne Drugs in Phase 1 and 2 Clinical Trials Expert opinion on investigational drugs · 2017
    4. 5-Alpha Reductase Deficiency Current Opinion in Endocrinology, Diabetes and Obesity · 2014
    5. Effect of Finasteride 5 mg (Proscar) on Acne and Alopecia in Female Patients with Normal Serum Levels of Free Testosterone Gynecological Endocrinology · 2007
    6. Treatment of Hyperandrogenic Alopecia in Women Fertility and Sterility · 2003
    7. A Comparison of the Relative Efficacy of Antiandrogens for the Treatment of Acne in Hyperandrogenic Women Clinical Endocrinology · 2002

    Related research 2

    1. Efficacy, Tolerability, and Safety of Montelukast Versus Finasteride for the Treatment of Moderate Acne in Women: A Prospective, Randomized, Single-Blinded, Active-Controlled Trial Journal of Cosmetic Dermatology · 2021
    2. Topical Antiandrogen Therapies for Androgenetic Alopecia and Acne Vulgaris American Journal of Clinical Dermatology · 2019