Anti-Acne Drugs in Phase 1 and 2 Clinical Trials

    June 2017 in “ Expert opinion on investigational drugs ”
    Christos C. Zouboulis, Clio Dessinioti, Fragkiski Tsatsou, Harald Gollnick
    Studysummary This review discusses ongoing and past trials for novel acne treatments, focusing on topical agents with potential sebosuppressive, antimicrobial, or anti-inflammatory effects, without reporting new clinical results.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
    Read the full study on tandfonline.com →
    Discuss this study in the Community →

    Research cited in this study 11

    1. Finasteride Adverse Effects in Subjects with Androgenic Alopecia: A Possible Therapeutic Approach According to the Lateralization Process of the Brain Journal of Dermatological Treatment · 2016
    2. Acne as a Chronic Systemic Disease Clinics in Dermatology · 2013
    3. Pharmacological Inhibition of Stearoyl CoA Desaturase in the Skin Induces Atrophy of the Sebaceous Glands ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2013
    4. New Pharmaceutical Concepts for Sebaceous Gland Diseases: Implementing Today's Pre-Clinical Data into Tomorrow's Daily Clinical Practice Current pharmaceutical biotechnology · 2012
    5. Acne-Associated Syndromes: Models for Better Understanding of Acne Pathogenesis Journal of The European Academy of Dermatology and Venereology · 2010
    6. Hormonal Therapy for Acne: Why Not as First Line Therapy? Facts and Controversies Clinics in Dermatology · 2009
    7. Biosynthesis of Dihydrotestosterone by a Pathway That Does Not Require Testosterone as an Intermediate in the SZ95 Sebaceous Gland Cell Line Journal of Investigative Dermatology · 2009
    8. Effect of Finasteride 5 mg (Proscar) on Acne and Alopecia in Female Patients with Normal Serum Levels of Free Testosterone Gynecological Endocrinology · 2007
    9. Cutaneous Androgen Metabolism: Basic Research And Clinical Perspectives ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2002
    10. Corticotropin-Releasing Hormone: An Autocrine Hormone That Promotes Lipogenesis in Human Sebocytes Proceedings of the National Academy of Sciences · 2002
    11. Sebocytes Are the Key Regulators of Androgen Homeostasis in Human Skin ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2001