What's New in Pediatric Dermatology?

The document reviewed recent advancements in pediatric dermatology as of 2017. Key findings included a comprehensive analysis of 541 trials on atopic dermatitis treatments, highlighting the efficacy of dermocorticoids and inhibitors. For alopecia areata, JAK inhibitors showed promise in case series, with 4 out of 6 children experiencing significant hair regrowth. Psoriasis research included a study comparing adalimumab and methotrexate in 114 children, while genetic mosaicism was confirmed in various skin conditions, influencing treatment approaches. Propranolol was effective for problematic hemangiomas in a study of 51 infants. Sirolimus showed modest to significant improvement in 19 patients with resistant lymphatic malformations. A new acne treatment, olumacostat glasaretil, was evaluated in a randomized trial with 108 patients, showing potential. For neurofibromatosis type 1, a decision tree was developed based on a study of 419 children with café au lait spots. Additionally, a flavored spray improved medication adherence in a small study of 25 children. Hyperthermia was found to enhance antiviral responses in HPV-infected cells. Lastly, a study on ichthyosis revealed a Th17-dominant inflammation, suggesting future trials with anti-IL-17 therapies.