What's New in Pediatric Dermatology?

    December 2017 in “ Annales de dermatologie et de vénéréologie ”
    C. Chiavérini
    TLDR In 2017, pediatric dermatology advanced with new treatments and insights into various skin conditions in children.
    The document reviewed recent advancements in pediatric dermatology as of 2017. Key findings included a comprehensive analysis of 541 trials on atopic dermatitis treatments, highlighting the efficacy of dermocorticoids and inhibitors. For alopecia areata, JAK inhibitors showed promise in case series, with 4 out of 6 children experiencing significant hair regrowth. Psoriasis research included a study comparing adalimumab and methotrexate in 114 children, while genetic mosaicism was confirmed in various skin conditions, influencing treatment approaches. Propranolol was effective for problematic hemangiomas in a study of 51 infants. Sirolimus showed modest to significant improvement in 19 patients with resistant lymphatic malformations. A new acne treatment, olumacostat glasaretil, was evaluated in a randomized trial with 108 patients, showing potential. For neurofibromatosis type 1, a decision tree was developed based on a study of 419 children with café au lait spots. Additionally, a flavored spray improved medication adherence in a small study of 25 children. Hyperthermia was found to enhance antiviral responses in HPV-infected cells. Lastly, a study on ichthyosis revealed a Th17-dominant inflammation, suggesting future trials with anti-IL-17 therapies.
    Discuss this study in the Community →

    Research cited in this study

    3 / 3 results

    Related Community Posts Join

    6 / 1000+ results

      community I am a dermatologist with a clinical interest in alopecia. AMA

      in Will treatment work for me? 2 years ago
      In this conversation, 4990 discussed various treatments for hair loss, including oral minoxidil, PRP, transplan, Jak inhibitors, Dutasteride, Finasteride, Olumiant, Ketoconazole, RU58841, microneedling, baricitinib, and CCCA. They recommended scalp biopsies in unclear cases of DUPA, twice weekly to twice daily shampooing for topical minoxidil users, and two sessions spaced one month apart with follow up at month three to determine the effectiveness of PRP treatment.

      community One+ year 1mg Fin, Ketoconazole, and 3.75 Oral Min. I have DUPA. Switched from Topical to Oral Min.

      in Progress Pictures  142 upvotes 2 years ago
      A user's experience with hair loss treatments such as finasteride, ketoconazole, and oral minoxidil that have not yielded any results; other users suggest shaving the head or getting a wig, while others offer additional advice such as seeing a dermatologist, checking thyroid levels, switching to dutasteride and adding needling, and trying stemoxydine.

      community What else is good. Besides the big 3.

      in Chat  34 upvotes 2 months ago
      Key treatments for hair preservation include minoxidil, finasteride/dutasteride, and microneedling, with additional options like specific shampoos, oils, biotin, zinc, tretinoin, clascoterone, and low-level laser therapy. Maintaining a healthy lifestyle, reducing stress, and addressing nutrient deficiencies can also support hair health.

      community Hair came back in 3 months at 39y/o.

      in Progress Pictures  421 upvotes 1 year ago
      A user shared their successful hair regrowth using a combination of minoxidil, caffeine, biotin, and RU58841, along with weekly dermarolling. However, others advised against the user's plan to switch to rosemary oil and microneedling only, emphasizing the importance of continuing the current treatment to maintain the results.

      community So we’re just ok with taking a research chemical now?

      in Treatment  181 upvotes 3 years ago
      The conversation discusses the use of RU58841, a non-FDA approved research chemical for hair loss, with mixed opinions on its safety and effectiveness. Some users are willing to try it as a last resort after other treatments like Minoxidil and Finasteride failed, while others express concerns about potential long-term side effects and lack of official research.

    Similar Research

    5 / 1000+ results