What's New in Pediatric Dermatology?

    December 2017 in “ Annales de dermatologie et de vénéréologie ”
    C. Chiavérini
    TLDR In 2017, pediatric dermatology advanced with new treatments and insights into various skin conditions in children.
    The document reviewed recent advancements in pediatric dermatology as of 2017. Key findings included a comprehensive analysis of 541 trials on atopic dermatitis treatments, highlighting the efficacy of dermocorticoids and inhibitors. For alopecia areata, JAK inhibitors showed promise in case series, with 4 out of 6 children experiencing significant hair regrowth. Psoriasis research included a study comparing adalimumab and methotrexate in 114 children, while genetic mosaicism was confirmed in various skin conditions, influencing treatment approaches. Propranolol was effective for problematic hemangiomas in a study of 51 infants. Sirolimus showed modest to significant improvement in 19 patients with resistant lymphatic malformations. A new acne treatment, olumacostat glasaretil, was evaluated in a randomized trial with 108 patients, showing potential. For neurofibromatosis type 1, a decision tree was developed based on a study of 419 children with café au lait spots. Additionally, a flavored spray improved medication adherence in a small study of 25 children. Hyperthermia was found to enhance antiviral responses in HPV-infected cells. Lastly, a study on ichthyosis revealed a Th17-dominant inflammation, suggesting future trials with anti-IL-17 therapies.
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      community I am a dermatologist with a clinical interest in alopecia. AMA

      in Will treatment work for me? 2 years ago
      In this conversation, 4990 discussed various treatments for hair loss, including oral minoxidil, PRP, transplan, Jak inhibitors, Dutasteride, Finasteride, Olumiant, Ketoconazole, RU58841, microneedling, baricitinib, and CCCA. They recommended scalp biopsies in unclear cases of DUPA, twice weekly to twice daily shampooing for topical minoxidil users, and two sessions spaced one month apart with follow up at month three to determine the effectiveness of PRP treatment.
      Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

      community Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

      in Research  865 upvotes 5 months ago
      The treatment for androgenetic alopecia involves using finasteride and minoxidil with intense exercise and cold exposure to boost metabolism and reduce androgenic effects, potentially leading to hair regrowth. This approach may activate biological pathways for improved hair and overall health.

      community any news about DUPA (Diffuse unpatterned alopecia)?

      in Research/Science  9 upvotes 2 years ago
      The conversation discusses diffuse unpatterned alopecia (DUPA) and its possible causes, including sensitivity to DHT, not being androgenic alopecia, being diffuse alopecia areata, or hormonal issues. Treatments mentioned include topical melatonin, Clobetasol Propionate for alopecia areata, and the lack of results from using finasteride, dutasteride, and minoxidil.

      community One+ year 1mg Fin, Ketoconazole, and 3.75 Oral Min. I have DUPA. Switched from Topical to Oral Min.

      in Progress Pictures  142 upvotes 2 years ago
      A user's experience with hair loss treatments such as finasteride, ketoconazole, and oral minoxidil that have not yielded any results; other users suggest shaving the head or getting a wig, while others offer additional advice such as seeing a dermatologist, checking thyroid levels, switching to dutasteride and adding needling, and trying stemoxydine.

      community What else is good. Besides the big 3.

      in Chat  35 upvotes 5 months ago
      Key treatments for hair preservation include minoxidil, finasteride/dutasteride, and microneedling, with additional options like specific shampoos, oils, biotin, zinc, tretinoin, clascoterone, and low-level laser therapy. Maintaining a healthy lifestyle, reducing stress, and addressing nutrient deficiencies can also support hair health.

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