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    Glossary Genetic Mosaicism

    presence of different genetic cell lines within one individual

    Genetic Mosaicism, also known simply as Mosaicism, refers to the presence of two or more genetically distinct cell lines within the same individual, originating from a single fertilized egg. This can result from mutations during cell division in early development, leading to some cells having different genetic makeup than others. This phenomenon can affect various tissues and organs, potentially leading to conditions like segmental vitiligo or certain forms of alopecia.

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    1. The Genetics of Human Skin Disease Cold Spring Harbor Perspectives in Medicine · 2014 · 24 citations
    2. Analogs of human genetic skin disease in domesticated animals International journal of women’s dermatology · 2017 · 3 citations
    3. Lichen planus pigmentosus and its variants: review and update International Journal of Dermatology · 2017 · 94 citations
    4. Distinct mechanisms underlie pattern formation in the skin and skin appendages Birth Defects Research · 2006 · 25 citations
    5. Quoi de neuf en dermatologie pédiatrique ? Annales de dermatologie et de vénéréologie · 2017
    6. Viewpoint 1 Experimental Dermatology · 2006
    7. Phylloid terminal hair nevus: A unique clinical entity Pediatric Dermatology · 2018
    8. British Society for Paediatric Dermatology Annual Meeting, Sheffield, 18-19 November 2016 British Journal of Dermatology · 2016
    9. Identification of somatic and germline mosaicism for a keratin 5 mutation in epidermolysis bullosa simplex in a family of which the proband was previously regarded as a sporadic case Clinical Genetics · 2004 · 26 citations
    10. Focal Scalp Hair Heterochromia in an Infant Sultan Qaboos University medical journal · 2017 · 2 citations
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