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research Identification of Somatic and Germline Mosaicism for a Keratin 5 Mutation in Epidermolysis Bullosa Simplex in a Family Initially Regarded as a Sporadic Case

26 citations , June 2004 in “Clinical Genetics”

The keratin 5 mutation in a family with epidermolysis bullosa simplex was due to mosaicism, not a new mutation.

research Bullous Congenital Ichthyosiform Erythroderma with Tinea Capitis in Half-Siblings: Rare Phenomenon in Ichthyosis with Co-Existing Trichophyton Rubrum Infection and Blocker Displacement Amplification for Mosaic Mutation Detection

August 2025 in “Biomedicines”

Half-siblings with a rare skin condition improved with treatment for a fungal infection, but hair loss remained.

De Novo Single-Nucleotide and Copy Number Variation in Discordant Monozygotic Twins Reveals Disease-Related Genes

research De Novo Single-Nucleotide and Copy Number Variation in Discordant Monozygotic Twins Reveals Disease-Related Genes

36 citations , March 2019 in “European Journal of Human Genetics”

The research found genetic differences in identical twins that could explain why one twin has a disease while the other does not.

research The Molecular Basis of Human Keratin Disorders

79 citations , February 2009 in “Human Genetics”

Acne Syndromes and Mosaicism

research Acne Syndromes and Mosaicism

1 citations , November 2021 in “Biomedicines”

Understanding how acne develops in different diseases could lead to new treatments.

View more "germline mosaicism" in research →

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community What should we lookout for in the near future for hairloss?

in Research/Science 17 upvotes 2 years ago

The user is using finasteride and minoxidil for hair loss but is looking for new treatments. Pyrilutamide and GT20029 are potential future treatments, with Pyrilutamide expected next year and GT20029 possibly by 2027.

community Please stop looking for a natural way to stop your hairloss

in Chat 247 upvotes 3 years ago

There is no natural way to stop hair loss; pharmaceuticals like minoxidil, finasteride, and RU58841 are the only effective treatments. Some users report success with minoxidil and microneedling, while others discuss the side effects of finasteride.