Prostate-Sparing Effects in Primates of the Potent Androgen 7α-Methyl-19-Nortestosterone: A Potential Alternative to Testosterone for Androgen Replacement and Male Contraception
December 1998
in “
The Journal of Clinical Endocrinology and Metabolism
”
7α-Methyl-19-Nortestosterone MENT testosterone luteinizing hormone LH serum lipids prostate growth androgen replacement therapy male contraception dihydrotestosterone DHT 5α-reductase androgenic alopecia acne testosterone luteinizing hormone LH serum lipids prostate growth androgen replacement therapy male contraception dihydrotestosterone DHT 5α-reductase androgenic alopecia acne
Studysummary This study found that MENT is 10 times more potent than testosterone in suppressing gonadotropins and contributing to anabolism in monkeys, with a potentially wider therapeutic index for human androgen replacement and male contraception.
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