Serum Testosterone Levels in Surgeons During Major Head and Neck Cancer Surgery: A Suppositional Study

This study investigated the effect of major head and neck cancer surgeries on serum testosterone levels in five male maxillofacial surgeons. It found that resting testosterone levels were similar among the surgeons (220 ± 120.9 mcg/ml). However, during the surgeries, there was a significant increase in testosterone levels, reaching up to 1062.50 mcg/ml. The increase was predicted by factors such as the size and extent of the tumor and the complexity of the microvascular reconstruction (all P<0.001). The study suggested that the long-term effects of elevated testosterone levels, which may be protective against conditions like Alzheimer's, warrant further investigation.