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The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

Early development of hair, teeth, and glands involves specific signaling pathways and cellular interactions.

Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.

Mice hair growth patterns get more complex with age and can change with events like pregnancy or injury.

Animals that change color with the seasons mainly do so in response to daylight changes, but climate change is causing camouflage problems that may require evolutionary changes.

Oxidative stress affects hair loss in men with androgenetic alopecia.

Skin can be cooled quickly and safely during laser treatments to protect it without affecting deeper layers.

Certain steroids in the brain affect mood and symptoms of depression, and treatments targeting these steroids show promise for improving these symptoms.

The circadian clock influences the behavior and regeneration of stem cells in the body.

Aging mice have slower hair regeneration due to changes in signal balance, but the environment, not stem cell loss, controls this, suggesting treatments could focus on environmental factors.

Technique creates 3D cell spheroids for hair-follicle regeneration.

Both drugs lower DHT levels, with GI198745 being more effective.

Environmental factors at different levels control hair stem cell activity, which could lead to new hair growth and alopecia treatments.

The research suggests that the global distribution of PCOS is likely due to historical human migration and that genes affecting PCOS may have different impacts on males and females.

Researchers developed a 3D model of human hair follicle cells that can help understand hair growth and test new hair loss treatments.

New sensor detects minoxidil accurately and effectively.

Scalp cooling can help prevent chemotherapy-induced hair loss with a 50-90% success rate and is safe for patients.

The document concludes that there is no clear definition of adequate health insurance, and a consistent method to measure underinsurance is needed.

Ethosomes improve drug delivery through the skin but may have side effects like irritation.

Inflammation plays a key role in activating skin stem cells for hair growth and wound healing, but more research is needed to understand how it directs cell behavior.

The 25Up study collected extensive data on mental disorders and related factors in Australian twins and siblings to investigate the genetics of psychiatric illnesses.

The document concludes that PK/PD modeling is important for determining the safe and effective dosages of drugs.

Micro-current stimulation may promote hair growth more effectively than standard treatments.

Some new isatin compounds could be strong cancer-fighting drugs because they fit well in cancer-related proteins and have good drug-like properties.

The document concludes that treating androgen excess needs patience, managing expectations is important, and many drugs used are not officially approved, suggesting cosmetic options for mild cases.

Quinoline alkaloids from Cinchona may help treat cancer, diabetes, fungal infections, and promote hair growth.

Combining light therapy and microneedling shows promise for treating female hair loss.

The study found no significant difference in stress hormone levels between people with alopecia areata and healthy individuals, suggesting that the disease is not caused by an overactive stress response system.

Hair follicle samples effectively show how well the drug MK-0752 targets and engages with the Notch pathway.