8 citations
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October 2024 in “Frontiers in Cell and Developmental Biology” This review suggests that telocytes in male reproductive organs help organize tissue structure and paracrine factors, impacting organ development and pathology, but more research is needed on their molecular pathways.
4 citations
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June 2025 in “Cell Reports” In this study using the C3H/HeJ mouse model of alopecia areata, researchers found that hyperexpanded CD8+ T cell clones were sufficient to initiate disease, establishing a causal link between T cell clonality and pathogenicity.
This study reviews the regulatory mechanisms and molecular processes governing stem cell activity in hair follicles, highlighting their roles in hair regeneration and potential implications for treating hair and skin disorders.
In this study, calcium imaging in transgenic mice revealed that non-neuronal TRPV4 in the skin enhances afferent signaling during electrical stimulation, suggesting a role for neuroimmune interaction in acupuncture signal initiation.
5 citations
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February 2022 in “Biophysical journal” This study developed a mathematical model indicating that the amino acid sequences of intermediate filament proteins, rather than flexibility differences, significantly impact assembly rates.
July 2024 in “Journal of Investigative Dermatology” 9 citations
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July 2020 in “Cell Proliferation” In this study, EREG promoted hair growth by activating specific receptors in cell and animal models, indicating it may be a potential treatment for hair loss.
January 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study found that Adapalene, Diosmin, and Azelastine have potential as multi-target drugs against Onchocerca volvulus and its endosymbiont, which might offer new therapeutic options for treating river blindness, but further research is needed to confirm their effectiveness.
September 2022 in “Journal of Theoretical Biology” This study developed a mathematical model to explore hair follicle regeneration mechanisms, showing that low spontaneous apoptosis rates help regenerate hair follicles after ionizing radiation, while high rates lead to degeneration during the catagen phase.
6 citations
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January 2021 in “Annals of Dermatology” This study found that 650-nm red light treatment promoted hair follicle proliferation and delayed the transition from anagen to catagen in ex vivo hair follicles from androgenetic alopecia patients, with RNA-seq analysis suggesting involvement of biological processes like metabolism and leukocyte migration.
3 citations
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July 2023 in “Frontiers in Aging” This research detailed a single-cell atlas showing dynamic hair follicle stem cell states associated with the hair cycle during aging in mice, highlighting differences in chromatin landscape linked to stem cell differentiation and quiescence, and providing a foundation for future exploration of aging reversal.
January 2026 in “Advances in Clinical Medicine”
February 2024 in “Current Bioactive Compounds” This study explored a novel finasteride-loaded nanoparticle gel for treating alopecia areata, finding that it significantly increased hair follicle number and size without causing skin irritation, presenting an effective alternative to traditional minoxidil treatments.
March 2022 in “Molecules” This study found that adenosine promotes hair growth by stimulating the Wnt/β-catenin pathway in cultured human dermal papilla cells through activation of the adenosine receptor.
August 2025 in “Processes” In this study, researchers used a network pharmacology approach to highlight significant interactions between compounds in rosemary (Salvia rosmarinus) and genes related to functional dyspepsia, suggesting potential pathways for developing treatments against gastrointestinal diseases.
December 2022 in “International Journal of Molecular Sciences” This study used machine learning to identify FDA-approved drugs afatinib, neratinib, and zanubrutinib as potential KRASG12C inhibitors for resistant non-small-cell lung cancer, highlighting the potential of AI in drug repurposing.
1 citations
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December 2022 in “Pharmaceuticals” This study found that a sub-fraction of Noni fruit, FEA-3, showed hair growth-promoting effects in a rabbit model of androgenic alopecia, similar to Minoxidil.
November 2025 in “Journal of Dermatological Treatment” Results are not reported in this abstract, which discusses a study evaluating the effects of platelet-rich plasma, minoxidil, and their combination on follicular metrics in androgenetic alopecia.
6 citations
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January 2025 in “Molecules” This review highlights the challenges in developing nano-scale drug delivery systems for natural antioxidants in wound healing, pointing out issues like low solubility and skin permeability, and discusses potential solutions such as combining polymers and lipids to enhance delivery effectiveness.
8 citations
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February 2025 in “Cell Systems” This study developed a genetic toolbox to engineer Cutibacterium acnes for dermal applications, successfully creating a strain that secretes antioxidants to reduce oxidative stress in a UV stress model.
319 citations
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March 2023 in “Science Advances” This study demonstrated that a wearable bioelectronic patch with combined therapy significantly accelerated chronic wound healing in a rodent model by monitoring and treating wounds noninvasively.
December 2025 in “eScience” This study presents a new wireless bioelectronic system powered by ambient Wi-Fi signals that enhances wound healing by providing electrical stimulation and real-time monitoring, offering a promising solution for at-home treatment and regenerative therapy.
40 citations
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September 2024 in “Heliyon” This review discusses the role of bioceramics, highlighting their bactericidal activity, lack of side effects, and ability to release metallic ions for hard and soft tissue repair. The authors suggest that integrating bioceramics with other biomaterials could offer a cost-effective, efficient alternative for wound healing.
3 citations
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July 2025 in “Current Issues in Molecular Biology” This review discusses how dental pulp stem cells and their derivatives may accelerate skin wound healing by modulating inflammation, promoting angiogenesis, optimizing extracellular matrix structure, and enhancing tissue formation, with implications for translating these findings into therapies for skin and mucosal repair.
1 citations
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February 2026 in “ACS Omega” This review highlights the potential of self-powered nanogenerators in revolutionizing biomedical devices by using biomechanical or environmental energy, focusing on applications like regenerative hair growth, drug release patches, and electronic skin while evaluating challenges such as energy efficiency and biocompatibility.
1 citations
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July 2025 in “Chemosensors” This study developed a closed-loop system for emergency wound care that monitors infection in real-time using biomarkers and delivers amikacin-loaded liposomes for treatment, integrating a conductive hydrogel for environmental protection and antibacterial benefits.
February 2026 in “International Journal of Molecular Sciences” In this review, researchers discuss how mitochondria-targeted biophysical priming of autologous biologics, through methods like photobiomodulation and ultrasound, can potentially enhance skin rejuvenation and wound repair by modulating mitochondrial function in skin cells.
September 2025 in “PubMed” This review discusses recent advances in hair regeneration strategies, including mechanical stimulation and complementary therapies like MSC transplantation and platelet-rich plasma, and reports no new clinical results.
October 2023 in “Biomaterials” This review highlights the potential of nanotechnology for hair follicle regeneration, focusing on strategies such as hair cycle modulation, progenitor cell stimulation, and wound-induced hair neogenesis, while also discussing regulatory challenges that may affect the development of these innovative approaches.
52 citations
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January 2023 in “Toxins” This narrative review discusses expert consensus on the optimal use of botulinum toxin injections for cosmetic applications in facial and oral-maxillofacial areas across Asian and Caucasian populations, highlighting injection techniques, effective doses, historical context, and potential complications.