Exploring Nanobioceramics In Wound Healing As Effective And Economical Alternatives

September 2024 in “ Heliyon ”

Hanan Adnan Shaker Al-Naymi, Mastafa H. Al‐Musawi, Marjan Mirhaj, Hamideh Valizadeh, Arefeh Momeni, Amir Mohammad Danesh Pajooh, Mina Shahriari‐Khalaji, Fariborz Sharifianjazi, Ketevan Tavamaishvili, Nafise Kazemi, Saeideh Salehi, Ahmadreza Arefpour, Mohamadreza Tavakoli

nanobioceramics oxide ceramics silicate-based ceramics calcium-phosphate ceramics angiogenesis cell stimulation antibacterial activity silver nitrate Al2O3 ZrO2 TiO2 cell proliferation macrophage polarization aluminum oxide zirconium dioxide titanium dioxide

TLDR Nanobioceramics can effectively and cheaply heal wounds without side effects.

The review discusses the potential of nanobioceramics as effective and economical alternatives for wound healing, emphasizing their biocompatibility and interaction with living tissues. It highlights three primary categories: oxide ceramics, silicate-based ceramics, and calcium-phosphate ceramics, which promote angiogenesis, cell stimulation, and antibacterial activity. These materials are cost-effective compared to expensive growth factors and pharmaceuticals, with silver nitrate being the most costly precursor at 5.8 USD per gram. Various nanoparticles, such as Al2O3, ZrO2, and TiO2, show promising wound healing capabilities, including enhanced cell proliferation and accelerated healing. The review also notes the potential of these materials in stimulating cell growth and modulating macrophage polarization, offering viable solutions for wound healing applications. Further research is encouraged to integrate bioceramics into wound treatment strategies.