Reconsidering Quantification and Mechanistic Inference in Platelet-Rich Plasma Research for Androgenetic Alopecia

November 2025 in “ Journal of Dermatological Treatment ”

Samuel Tringali

platelet-rich plasma minoxidil androgenetic alopecia follicular dynamics neogenesis hypertrophic changes microvascular remodeling PRP Rogaine AGA

From the encyclopedia

Platelet-Rich Plasma →

growth factors taken from your blood and injected into your scalp to stimulate hair

Minoxidil →

An essential vasodilator with some anti-androgenic effects

Studysummary Results are not reported in this abstract, which discusses a study evaluating the effects of platelet-rich plasma, minoxidil, and their combination on follicular metrics in androgenetic alopecia.

Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer

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Research cited in this study

5 / 5 results

Effects of Platelet-Rich Plasma on Hair Follicle Count and Hair Ratios in Androgenic Alopecia: Alone or Combined with Other Treatments

research Effects of Platelet-Rich Plasma on Hair Follicle Count and Hair Ratios in Androgenic Alopecia: Alone or Combined with Other Treatments

July 2025 in “Journal of Dermatological Treatment”

This study found that platelet-rich plasma significantly improved hair growth parameters in androgenic alopecia patients and was even more effective when combined with minoxidil, particularly in reducing vellus hair.

The Additive Value of Platelet-Rich Plasma to Topical Minoxidil in the Treatment of Androgenetic Alopecia: A Systematic Review and Meta-Analysis

research The Additive Value of Platelet-Rich Plasma to Topical Minoxidil in the Treatment of Androgenetic Alopecia: A Systematic Review and Meta-Analysis

August 2024 in “PLoS ONE”

This study reviewed randomized controlled trials to assess whether adding platelet-rich plasma injections to a Minoxidil regimen offers any benefit in treating androgenetic alopecia, but results are not reported in the abstract.

research Platelet-Rich Plasma for Androgenetic Alopecia: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

2 citations , August 2023 in “Journal of Cutaneous Medicine and Surgery”

This study concluded that platelet-rich plasma is effective and safe for increasing hair density in androgenetic alopecia, showing significant improvement compared to placebo at 3 and 6 months.

Randomized Placebo-Controlled, Double-Blind, Half-Head Study to Assess the Efficacy of Platelet-Rich Plasma on the Treatment of Androgenetic Alopecia

research Randomized Placebo-Controlled, Double-Blind, Half-Head Study to Assess the Efficacy of Platelet-Rich Plasma on the Treatment of Androgenetic Alopecia

136 citations , April 2016 in “Dermatologic Surgery”

This study found that platelet-rich plasma significantly increased hair density and anagen hair proportions in androgenetic alopecia patients, suggesting potential as an adjuvant therapy.

research Autologous Platelet-Rich Plasma: A Potential Therapeutic Tool for Promoting Hair Growth

270 citations , March 2012 in “Dermatologic Surgery”

This study found that autologous platelet-rich plasma increased hair growth potential by enhancing dermal papilla cell proliferation and stimulating key signaling pathways in both cell cultures and mice models.