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This article reviews the potential neuroprotective effects of 17α‐estradiol in neurodegenerative diseases and highlights its possibly lower toxicity compared to more feminizing hormones, but it reports no new clinical findings.

This study suggests that sinapic acid may promote hair growth in human hair follicle dermal papilla cells by activating specific signaling pathways and inducing the expression of growth factors.

This study reported that baicalin activates the Wnt/β-catenin signaling pathway in mouse hair follicles, suggesting its potential as a topical treatment for hair loss.

This study demonstrated that a 3D air–liquid culture system using Wnt-CM-treated cells can induce hair regeneration in nude mice and may facilitate large-scale preparation for hair loss treatment.

This review discusses the potential of nanotechnology-based formulations for delivering topical minoxidil to improve hair loss treatment outcomes and reports no new clinical results, urging further research into their benefits and safety considerations.

This review discusses various approaches to treating alopecia, including drug therapy and hair transplantation, but reports no new research findings; the authors highlight the need for novel techniques like cell culturing.

This study found that micro-current electrical stimulation may promote hair growth in human hair follicle-derived papilla cells and a mice model by enhancing cell proliferation, migration, and activating key growth pathways.

This study suggests that Houttuynia cordata extract may promote hair growth by stimulating dermal papilla cell proliferation and extending the anagen phase through enhanced energy metabolism and gene expression changes.

This study reported that a novel chitosan/polyvinyl alcohol nanofiber sponge effectively enhances the hair follicle-inducing ability of dermal papilla multicellular spheroids in a mouse model.

This study found that Centipeda minima extract promotes hair growth by activating Wnt/β-catenin, ERK, and JNK signaling pathways in human hair follicle dermal papilla cells.

This study found that ethanol extract of Tubtim Chumphae rice bran downregulates SRD5A gene expression, similarly to finasteride, suggesting potential use as an anti-hair loss product.

This review article summarizes the potential role of advanced medical therapies—using genes, cells, and/or tissue engineering—in treating various types of alopecia, by examining clinical research, basic studies, and ongoing trials.

This study found that neural stem cell extract enhanced hair growth in mice and cells by stimulating hair follicle niches and activating signaling pathways like TGF-β and BMP.

In this study using a mouse model, ECM/SVF-CM, derived from adipose-derived stem cells, was observed to stimulate hair growth more effectively than SVF-CM by promoting cell proliferation, neovascularization, and anagen induction, which may support its potential as an improved treatment for hair loss.

This study found that plasma rich in growth factors (PRGF) as an adjuvant to follicular unit extraction (FUE) surgery may enhance hair graft performance and reduce post-surgical inflammation and pain in hair loss patients.

This study found that combining plasma rich in growth factors with conventional treatment significantly improved hair regrowth and reduced symptoms in patients with frontal fibrosing alopecia compared to conventional treatment alone.

This study found that mycophenolate may stabilize β-catenin and counteract interferon-γ-induced catagen changes in human dermal papilla cells, which could promote hair growth.

This study used single-cell RNA sequencing to map the cellular composition of sheep hair follicles, revealing differentiation pathways and potential molecular mechanisms for wool curvature, which may inform sheep breeding.

Both methods improve hair density and thickness; double-spin may be more effective.

In this study, selenium-rich diets enhanced antioxidant activity in aged mice, suggesting potential biological benefits, although further trials are needed to fully understand long-term risks and benefits.

This study found that the interaction between heat shock protein 90 and lamin A/C is crucial for the growth, migration, and self-aggregation of dermal papilla cells, suggesting a potential role in alopecia areata mechanisms.

This study found that stress hormones, particularly CRF, can inhibit hair growth and induce hair loss by affecting human dermal papilla cells and hair follicles, suggesting a functional HPA axis in these cells.

This study found that applying HHORSC exosomes may enhance the hair inductivity of dermal papilla cells, potentially improving treatments for hair loss.

This review assessed experimental studies on herbs used for alopecia, identifying potential mechanisms involving hair cycle management and keratinocyte processes, but highlighted a need for improved evidence on quality control and toxicity of these herbal treatments.

This study found that Rumex japonicus Houtt. root extract promoted hair growth by enhancing cell proliferation and preventing apoptosis in human dermal papilla cells and HaCaT cells, as well as in a mouse model.

This study found that PGA-4HGF nanoparticles enhanced hair growth in mice more effectively than 4HGF alone by increasing anagen phase duration and dermal papilla cell proliferation.

In this study, extracts from three Polynesian plants—Bidens pilosa, Calophyllum inophyllum, and Fagraea berteroana—were found to increase dermal papilla cell proliferation and modulate hair growth-related gene expression, suggesting potential for stimulating hair growth.

This review reported that tripeptides, such as GHK and KdPT, show promise in enhancing wound healing through multiple mechanisms, including promoting cell migration, collagen deposition, and angiogenesis, while offering antimicrobial and anti-inflammatory benefits for both acute and chronic wounds.

This abstract discusses the role of advanced glycation end-products in aging-related skin damage, but does not provide new findings on their impact on alopecia.

This review discusses the mechanisms of hair repigmentation and reports no clinical results; the authors suggest further research into topical treatments for reversing gray hair.