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330-360 / 694 resultsresearch Skin‐on‐a‐chip strategies for human hair follicle regeneration
research Bioengineered polyester nanoparticles for the synergistic treatment of androgenic alopecia via the suppression of 5α-reductase and knockdown of androgen receptor
![SKPs Derive from Hair Follicle Precursors and Exhibit Properties of Adult Dermal Stem Cells](/images/research/ab47001e-2ad4-4c35-9270-c7d4f3627b8e/small/29369.jpg)
research SKPs Derive from Hair Follicle Precursors and Exhibit Properties of Adult Dermal Stem Cells
SKPs are similar to adult skin stem cells and could help in skin repair and hair growth.
![Cultured Peribulbar Dermal Sheath Cells Can Induce Hair Follicle Development and Contribute to the Dermal Sheath and Dermal Papilla](/images/research/b859a9f0-990d-471a-b54e-eea92166516d/small/20026.jpg)
research Cultured Peribulbar Dermal Sheath Cells Can Induce Hair Follicle Development and Contribute to the Dermal Sheath and Dermal Papilla
Certain cells from hair follicles can create new hair and contribute to hair growth when implanted in mice.
![Lenalidomide Augments Differentiation of Cultured Hair Follicle Derived Melanocyte Stem Cells Into Functional Melanocytes](/images/research/0608d6b2-f80e-4b3b-84ba-1b14688d793c/small/31004.jpg)
research Lenalidomide Augments Differentiation of Cultured Hair Follicle Derived Melanocyte Stem Cells Into Functional Melanocytes
Lenalidomide helps hair follicle stem cells turn into melanocytes, which may improve repigmentation in vitiligo.
![The Keratins of the Human Beard Hair Medulla: The Riddle in the Middle](/images/research/bcb99fbe-4b30-49f2-9392-9a5e5fa7bd2b/small/29353.jpg)
research The Keratins of the Human Beard Hair Medulla: The Riddle in the Middle
Human beard hair medulla contains a unique and complex mix of keratins not found in other human tissues.
![Human Scalp Hair Follicles Are Both a Target and a Source of Prolactin, which Serves as an Autocrine and/or Paracrine Promoter of Apoptosis-Driven Hair Follicle Regression](/images/research/4b31122f-6a4b-4d91-bb8f-28bc61d3c10f/small/21026.jpg)
research Human Scalp Hair Follicles Are Both a Target and a Source of Prolactin, which Serves as an Autocrine and/or Paracrine Promoter of Apoptosis-Driven Hair Follicle Regression
Prolactin contributes to hair loss by promoting hair follicle shrinkage and cell death.
![A new path in defining light parameters for hair growth: Discovery and modulation of photoreceptors in human hair follicle](/images/research/38f09f13-c7b3-40e4-998c-776d635d6f1a/small/32199.jpg)
research A new path in defining light parameters for hair growth: Discovery and modulation of photoreceptors in human hair follicle
Blue light promotes hair growth by interacting with specific receptors in hair follicles.
![Glutamine Metabolism Controls Stem Cell Fate Reversibility and Long-Term Maintenance in the Hair Follicle](/images/research/abc073bc-3c5c-4425-af5e-c5b1aff5162b/small/19270.jpg)
research Glutamine Metabolism Controls Stem Cell Fate Reversibility and Long-Term Maintenance in the Hair Follicle
Glutamine metabolism affects hair stem cell maintenance and their ability to change back to stem cells.
![Tooth, hair and claw: Comparing epithelial stem cell niches of ectodermal appendages](/images/research/35cf3a6b-4b57-42f2-afda-acddd94fd699/small/19722.jpg)
research Tooth, hair and claw: Comparing epithelial stem cell niches of ectodermal appendages
The conclusion is that teeth, hair, and claws have similar stem cell niches, which are important for growth and repair, and more research is needed on their regulation and potential markers.
research Dissecting the Impact of Chemotherapy on the Human Hair Follicle
Chemotherapy damages hair follicles, causing hair loss and other cellular changes.
![Enriching Proteolysis Targeting Chimeras with a Second Modality: When Two Are Better Than One](/images/research/83cefa28-6196-4fa8-b7ac-d02826740e94/small/16903.jpg)
research Enriching Proteolysis Targeting Chimeras with a Second Modality: When Two Are Better Than One
Adding a second method to PROTACs could improve cancer treatment.
research Five‐year experience in the treatment of alopecia areata with DPC
Diphencyprone (DPC) is an effective and safe long-term treatment for alopecia areata, especially with maintenance therapy.
![Treatment of androgenetic alopecia by exosomes secreted from hair papilla cells and the intervention effect of LTF](/images/research/1f0bed00-8366-4baa-9f33-764689959396/small/12899.jpg)
research Treatment of androgenetic alopecia by exosomes secreted from hair papilla cells and the intervention effect of LTF
Exosomes from hair papilla cells and the Chinese medicine Liao Tuo Fang can potentially promote hair growth and could be used to develop hair growth drugs.
![1333 Spheroids cell cultures as a promising study model for hair follice regeneration](/images/research/af8f29ae-742c-4183-847e-5e4c46727a00/small/12738.jpg)
research 1333 Spheroids cell cultures as a promising study model for hair follice regeneration
Culturing Dermal Papilla Cells and Hair Follicle Stem Cells in 3D conditions can significantly improve hair regeneration potential.
research Biological characterization of cultured dermal papilla cells tnd hair follicle regeneration in vitro and in vivo
Cultured skin cells can trigger hair growth and the amount of certain proteins they produce affects their ability to regenerate hair follicles.
![Dermal papilla cell-derived exosomes promote hair follicle regeneration during wound healing by activating Wnt/β‐catenin signaling pathway](/images/research/cfdb16ec-67a4-4819-a06c-d9dc0025a19f/small/26431.jpg)
research Dermal papilla cell-derived exosomes promote hair follicle regeneration during wound healing by activating Wnt/β‐catenin signaling pathway
Tiny particles from skin cells can help grow new hair by activating a specific growth signal during skin healing.
research Exosomes derived from dermal papilla cells mediate hair follicle stem cells proliferation through the Wnt3a/β-catenin signaling pathway
Exosomes from dermal papilla cells help hair stem cells grow through a specific signaling pathway.
research Exosomal miRNA-181a-5p from the cells of the hair follicle dermal papilla promotes the hair follicle growth and development via the Wnt/β-catenin signaling pathway
miR-181a-5p helps hair growth by activating a specific signaling pathway.
![Direct Reprograming of Mouse Fibroblasts into Dermal Papilla Cells via Small Molecules](/images/research/35e97991-b167-4def-805d-745851e85df0/small/19193.jpg)
research Direct Reprograming of Mouse Fibroblasts into Dermal Papilla Cells via Small Molecules
Scientists turned mouse skin cells into hair-inducing cells using chemicals, which could help treat hair loss.
![592 Cross-interactions of BMP and WNT signaling pathways attenuate androgen effect on HFSC differentiation](/images/research/0f75c969-d251-461a-b19f-78e24bc05e24/small/17615.jpg)
research 592 Cross-interactions of BMP and WNT signaling pathways attenuate androgen effect on HFSC differentiation
BMPs are important for hair growth and can counteract the negative effects of androgens on hair follicle stem cells.
![The use of diphencyprone in dermatology: A retospective audit](/images/research/07aa519b-0ec8-4e15-adc0-f6751c9b8fa7/small/15289.jpg)
research The use of diphencyprone in dermatology: A retospective audit
Diphencyprone treatment protocols could be simplified as no harm occurred despite not fully following them.
![Dermal PapillaCell-Derived Exosomes Regulate Hair Follicle Stem Cell Proliferation via LEF1](/images/research/6db3cbc9-52eb-42bb-bfdc-224d5ebbb8b1/small/6181.jpg)
research Dermal PapillaCell-Derived Exosomes Regulate Hair Follicle Stem Cell Proliferation via LEF1
Exosomes from skin cells can boost hair growth by stimulating a gene called LEF1.
![Vitamin A regulates dermal papilla cell proliferation and apoptosis under heat stress via IGF1 and Wnt10b signaling](/images/research/945f358e-2817-4fa5-b841-56176c6d8878/small/31246.jpg)
research Vitamin A regulates dermal papilla cell proliferation and apoptosis under heat stress via IGF1 and Wnt10b signaling
Vitamin A helps rabbit skin cells grow and survive heat stress.
![Effect and mechanism of Docosahexaenoic acid on the proliferation of dermal papilla cells](/images/research/c9585505-3468-4683-aa37-2e457939be5e/small/31792.jpg)
research Effect and mechanism of Docosahexaenoic acid on the proliferation of dermal papilla cells
Docosahexaenoic acid (DHA) may help hair growth by promoting dermal papilla cell proliferation.
![Minoxidil upregulates the expression of vascular endothelial growth factor in human hair dermal papilla cells](/images/research/74c1d571-2495-41f3-900d-053081982a9b/small/2186.jpg)
research Minoxidil upregulates the expression of vascular endothelial growth factor in human hair dermal papilla cells
Minoxidil boosts growth factor in hair cells, potentially promoting hair growth.
![Self-assembly of dermal papilla cells into inductive spheroidal microtissues on poly(ethylene-co-vinyl alcohol) membranes for hair follicle regeneration](/images/research/b0ed04d4-1725-4943-9f3b-709dfa98bf1f/small/2813.jpg)
research Self-assembly of dermal papilla cells into inductive spheroidal microtissues on poly(ethylene-co-vinyl alcohol) membranes for hair follicle regeneration
EVAL membranes help create cell structures that can regrow hair follicles.
![Development, Structure, and Keratin Expression in <i>C57BL/6J</i> Mouse Eccrine Glands](/images/research/657c734d-0a08-49fc-ba3e-bdc319b53744/small/29286.jpg)
research Development, Structure, and Keratin Expression in C57BL/6J Mouse Eccrine Glands
The study found that mouse sweat glands develop before birth, mature after birth, and have specific keratin patterns.
![Testosterone Metabolism in Human Skin Cells in vitro and Its Interaction with Estradiol and Dutasteride](/images/research/7515b3d4-70e3-48c5-af9f-1b01489161df/small/28706.jpg)
research Testosterone Metabolism in Human Skin Cells in vitro and Its Interaction with Estradiol and Dutasteride
Different skin cells process testosterone differently, and certain drugs can change this process, possibly helping treat acne and hair loss.