Whole-Genome Resequencing Reveals Selection Signal Related to Sheep Wool Fineness

    September 2023 in “ Animals ”
    Wentao Zhang, Meilin Jin, Taotao Li … Caihong Wei
    Studysummary In this study, researchers conducted whole-genome resequencing of eight sheep breeds to identify additional genes associated with wool fineness, revealing 269 genes in fine wool and 319 in coarse wool breeds that are linked to significant traits and pathways.
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    Research cited in this study 23

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    4. Hedgehog Signaling Reprograms Hair Follicle Niche Fibroblasts to a Hyper-Activated State Developmental cell · 2022
    5. Identification of Key Genes and Signaling Pathways Related to Hetian Sheep Wool Density by RNA-Seq Technology PLOS ONE · 2022
    6. Single-Cell Transcriptomics Reveals the Molecular Anatomy of Sheep Hair Follicle Heterogeneity and Wool Curvature Frontiers in cell and developmental biology · 2021
    7. Evidence for a Functional Interaction of WNT10A and EBF1 in Male-Pattern Baldness PLoS ONE · 2021
    8. Comprehensive Transcriptome and Methylome Analysis Delineates the Biological Basis of Hair Follicle Development and Wool-Related Traits in Merino Sheep BMC Biology · 2021
    9. Dermal EZH2 Orchestrates Dermal Differentiation and Epidermal Proliferation During Murine Skin Development Developmental biology · 2021
    10. Dihydrotestosterone-Induced Hair Regrowth Inhibition by Activating Androgen Receptor in C57BL6 Mice Simulates Androgenetic Alopecia Biomedicine & Pharmacotherapy · 2021
    11. EZH2-Mediated Inhibition of MicroRNA-22 Promotes Differentiation of Hair Follicle Stem Cells by Elevating STK40 Expression Aging · 2020
    12. Androgens and Androgen Receptor Action in Skin and Hair Follicles Molecular and Cellular Endocrinology · 2017
    13. Evaluation of Gene Expression Patterns in Micrografts Demonstrates Induction of Catagen-Like Processes During Storage Dermatologic Surgery · 2017
    14. Hair Curvature: A Natural Dialectic and Review Biological reviews/Biological reviews of the Cambridge Philosophical Society · 2014
    15. Genome-Wide Association Study Identifies a New Locus JMJD1C at 10q21 That May Influence Serum Androgen Levels in Men Human molecular genetics online/Human molecular genetics · 2012
    16. Deficiency in Nucleotide Excision Repair Family Gene Activity, Especially ERCC3, Is Associated with Non-Pigmented Hair Fiber Growth PloS one · 2012
    17. Inducible Deletion of Epidermal Dicer and Drosha Reveals Multiple Functions for miRNAs in Postnatal Skin Development · 2012
    18. Activation of Beta-Catenin Signaling Programs Embryonic Epidermis to Hair Follicle Fate Development · 2008
    19. Selective Modulation of Hedgehog/GLI Target Gene Expression by Epidermal Growth Factor Signaling in Human Keratinocytes Molecular and Cellular Biology · 2006
    20. K25 (K25irs1), K26 (K25irs2), K27 (K25irs3), And K28 (K25irs4) Represent The Type I Inner Root Sheath Keratins Of The Human Hair Follicle Journal of Investigative Dermatology · 2006
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