Evaluation of Gene Expression Patterns in Micrografts Demonstrates Induction of Catagen-Like Processes During Storage

January 2017 in “ Dermatologic Surgery ”

Walter Krugluger, Karl Stiefsohn, Karl Moser, Claudia Moser, Katarina Laciak

hair follicle micrografts hair restoration surgery dermal papilla cells FGF7 versican alkaline phosphatase catagen-like state hair follicle cycle keratin genes gene expression growth differentiation apoptosis hair transplants DP cells ALP

Studysummary This study observed that storing hair follicle micrografts significantly decreased the expression of certain key genes in the dermal papilla, potentially affecting hair follicle cycling during preparation and storage.

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research A Review of Cellular Biopreservation Considerations During Hair Transplantation

18 citations , January 2013 in “International Society of Hair Restoration Surgery”

This article discusses the importance of clinical biopreservation for cells and tissues in hair transplantation and regenerative medicine, reporting no new empirical findings.

research New Activators and Inhibitors in the Hair Cycle Clock: Targeting Stem Cells’ State of Competence

68 citations , April 2012 in “Journal of Investigative Dermatology”

The study reports that Fgf18 and Tgf-β2 signaling pathways in hair follicle stem cells have opposing effects on the timing of hair cycle transitions, influencing the shift from telogen to anagen phases.

Developing New Graft Holding Solutions: In Vitro Evaluation of Bioactive Molecules Identifies Vitamin B12 as Micrograft Stabilizing Substance

research Developing New Graft Holding Solutions: In Vitro Evaluation of Bioactive Molecules Identifies Vitamin B12 as Micrograft Stabilizing Substance

8 citations , January 2007 in “Hair transplant forum international”

This abstract reviews recent findings on the biology of isolated micrografts in hair restoration, emphasizing factors that enhance micrograft viability, but it does not report new experimental results.

research Hair Cycle-Specific Expression of Versican in Human Hair Follicles

88 citations , May 2005 in “Journal of Dermatological Science”

In this study, specific versican expression was observed in the anagen phase of human hair follicles, suggesting its importance in maintaining normal hair growth.

research New Storage Buffers for Micrografts Enhance Graft Survival and Clinical Outcome in Hair Restoration Surgery

8 citations , May 2003 in “Hair transplant forum international”

This article discusses the importance of preparing and storing human hair follicle grafts during micrograft transplantation in hair restoration surgery and reports no new research findings.

research Effects of Cooling Micrografts in Hair Transplantation Surgery

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This study found that cooling hair grafts during transplantation did not significantly improve the survival or growth rates of hair follicles compared to room temperature storage.

research The Biology of Hair Follicles

1113 citations , August 1999 in “The New England Journal of Medicine”

This article discusses the biologic and psychosocial significance of hair, the current limitations in hair growth drugs, and anticipates future therapies based on advancing hair follicle research.

research Power Boosting the Grafts in Hair Transplantation Surgery

22 citations , December 1998 in “Dermatologic Surgery”

This study found that preserving hair micrografts in an enriched storage medium for five hours significantly increased their survival rate compared to those stored in saline.

Characterization and Chromosomal Localization of Human Hair-Specific Keratin Genes and Comparative Expression During the Hair Growth Cycle

research Characterization and Chromosomal Localization of Human Hair-Specific Keratin Genes and Comparative Expression During the Hair Growth Cycle

32 citations , February 1998 in “The journal of investigative dermatology/Journal of investigative dermatology”

This study reports the cloning and sequencing of two type II hair-specific keratin genes, ghHb1 and ghHb6, located on chromosome 12q13, which are expressed during hair growth.

research Standardized Technique of Transplanting Micrografts in Hair Restoration Surgery

9 citations , September 1997 in “Dermatologic Surgery”

In this paper, the authors describe a standardized micrografting technique for hair transplantation that significantly speeds up the procedure and minimizes surgical trauma, enhancing graft survival.

research Regulation of Keratin Gene Expression in Hair Follicle Differentiation

98 citations , December 1991 in “Annals of the New York Academy of Sciences”

This study found that conserved DNA motifs and expression patterns in keratin genes suggest functional regulatory similarities in hair follicle differentiation across different mammalian species.