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This study highlights the challenges in treating Microsporum canis infections due to variable antifungal drug efficacy and potential resistance, emphasizing the need for standardized methods to assess drug susceptibility.

This study found that newly synthesized steroidal trienones demonstrated stronger 5α-reductase inhibitory activity compared to dienones in various biological models, suggesting potential for developing enhanced antiandrogenic drugs.

This study found that nanoemulsions incorporating skin penetration enhancers significantly increased the permeation of minoxidil through human skin compared to aqueous control solutions.

This study found that the contribution of the hair follicle pathway to skin permeation of chemicals can be predicted using lipophilicity, with hydrophilic chemicals showing greater permeation reduction from hair follicle plugging than lipophilic ones.

This study found that increasing the proportion of ethanol in minoxidil formulations improved skin penetration in both in vitro and in vivo tests on mice.

This study found that coating liquid crystalline nanoparticles with chitosan significantly enhanced the skin permeation of 5α-reductase inhibitors, suggesting a promising strategy for improving topical delivery in androgenetic alopecia treatment.

This study found that using drug microplates in transdermal finasteride films enhances aqueous solubility and skin permeation compared to films with pure finasteride.

This study identified a weak interaction between minoxidil and ß-cyclodextrin in solution, forming an inclusion complex with a 1:1 molar ratio.

This study found that solid lipid nanoparticles with minoxidil were as effective as commercial solutions for skin penetration and were non-corrosive, indicating potential for hair loss treatment.

Method measures minoxidil in tablets accurately and easily.

In this study, Gaussian process regression models combined with Grey Wolf optimization were used to predict and optimize phenolic and flavonoid content extraction from Carthamus caeruleus L. rhizomes, showing high accuracy and helping improve understanding and extraction processes through a new interactive tool.

This study found that pretreating mouse skin with microneedles significantly enhanced the hair growth inhibitory effect of eflornithine cream, likely by improving its skin permeation.

This review discusses iontophoresis, low-frequency ultrasound, and microneedles for enhancing topical drug delivery in dermatological treatments and reports no clinical results; it emphasizes their mechanisms and potential uses.

This study suggests that gel containing OSF3 loaded in niosomes offers high transfollicular penetration for topical anti-androgenic alopecia treatment with minimal systemic effect.

This research investigated aqueous alginate-based hydrogels for delivering minoxidil and reported that using hydroxypropyl-β-cyclodextrin (HP-β-CD) with molar substitution 0.65 significantly enhanced minoxidil's solubility and skin permeability without damaging the epidermis, suggesting potential as an alternative to commercial minoxidil solutions.

In this study, the researchers observed that the transdermal permeation mechanisms of diclofenac salts differ based on counterions, with varying pathways and routes for passive and iontophoretic transport.

This study evaluated new aqueous gel formulations of minoxidil without irritants and found that the calcium alginate gel showed the best performance in terms of drug release and skin permeation.

This study investigated lipid loss in hair caused by surfactants and found that surface and internal modifications can significantly protect different lipids from depletion, with internal modification preventing 52.0 to 81.3% of lipids in certain groups.

This study found that a 2% polyherbal phyto-complex cream containing aqueous extracts of Trichosanthes cucumerina and Abrus precatorius effectively promoted hair growth in preclinical tests, comparable to minoxidil 2%.

This study found that invasomes enhanced the iontophoretic transdermal delivery of finasteride in rabbits, increasing AUC and T1/2 compared to oral suspension.

This study found that cold air can effectively preserve the epidermis when using an 810 nm diode laser, but it is slightly less effective than a chilled sapphire window in dark-haired pigmented pigs.

This study found that co-applying Curcuma aeruginosa extract or essential oil with minoxidil significantly increased minoxidil's skin penetration in an ex vivo setting, suggesting an improved topical treatment strategy for androgenic alopecia with greater efficacy and the potential for lower minoxidil doses.

This study found that dual-frequency ultrasound with microbubble cavitation significantly enhanced minoxidil delivery and hair growth in both lab and animal models compared to single-frequency ultrasound, without damaging the skin in mice.

This study validated the differential stripping technique on hairless rat skin and found that the P-08–016 formulation delivered more finasteride to the epidermis and appendages compared to P-10–008.

This study examined the pharmacokinetics of finasteride in pigs and found that ketoconazole coadministration affected its distribution across various plasma compartments, bile, and urine.

This study found that finasteride- and dutasteride-loaded iron oxide nanoparticles improved drug penetration in the skin, suggesting they may be promising for topical alopecia therapies.

This paper introduces an algorithm for using smart device-mounted microscopes to analyze scalp images and diagnose hair loss by extracting specific hair loss features.

This study suggests that a microemulsion formulation of Minoxidil effectively enhances drug delivery through hair follicles, showing significant follicular response alterations in an alopecia model.

This research found that ethosomes significantly enhanced finasteride delivery into the dermis of human cadaver skin compared to liposomes in an in vitro study.

This review highlights the potential of nanoemulgel as a promising drug delivery system for lipophilic drugs, but presents no new experimental results; it discusses composition, preparation methods, and applications.