Prevention of Lipid Loss from Hair by Surface and Internal Modification

July 2019 in “ Scientific reports ”

Sang-Hun Song, Jong Hyun Lim, Seong Kil Son, Jaehyun Choi, Nam Lyong Kang, Sangmin Lee

lipid loss hair surfactants surface modification internal modification cationic polymers fatty acids cholesterol carbodiimide reaction squalene wax esters amphipathic lipids hydrophobic lipids

Studysummary This study investigated lipid loss in hair caused by surfactants and found that surface and internal modifications can significantly protect different lipids from depletion, with internal modification preventing 52.0 to 81.3% of lipids in certain groups. Our plain-language summary of this paper — not a Tressless recommendation.

The study investigated methods to prevent lipid loss from hair caused by surfactants during washing, focusing on surface and internal modifications. Surface modification with highly charged cationic polymers reduced the loss of fatty acids and cholesterol by 22-32%, while internal modification using a carbodiimide reaction prevented 52.0-81.3% of squalene and wax esters from being lost. The study concluded that different lipids are affected by distinct mechanisms, with surface treatments primarily preventing the loss of amphipathic lipids and internal modifications effectively retaining hydrophobic lipids. The findings provided insights into surfactant-induced lipid loss and suggested strategies for protecting hair lipids.

View this study on nature.com →

Discuss this study in the Community →

Research cited in this study

7 / 7 results

research Investigation of pH Effect on Cationic Solute Binding to Keratin and Partition to Hair

3 citations , November 2017 in “International Journal of Cosmetic Science”

This study found that increasing the pH from 2.0 to 6.0 enhanced the binding of cationic solutes to hair keratin, driven primarily by hydrophobic and electrostatic interactions.

research Effect of a Peptide in Cosmetic Formulations for Hair Volume Control

14 citations , July 2017 in “International Journal of Cosmetic Science”

This study found that Caucasian hair experienced greater volume changes than Asian hair in various relative humidity conditions, and incorporating a peptide into climate control formulations significantly reduced hair volume, particularly in high humidity settings.

research Keratin Network Modifications Lead to the Mechanical Stiffening of the Hair Follicle Fiber

40 citations , May 2016 in “Proceedings of the National Academy of Sciences of the United States of America”

This study found that the mechanical stiffening of the human hair follicle along the first millimeter is linked to changes in the keratin network architecture and composition during keratinization.

research Discovery of a Sol–Gel Reinforcing the Strength of Hair Structure: Mechanisms of Action and Macroscopic Effects on the Hair

2 citations , February 2016 in “Journal of sol-gel science and technology”

This study found that 3-aminopropyltriethoxysilane penetrates hair fibers and improves the mechanical resistance of dry hair, addressing the needs for increased body in fine hair.

research Distribution of Glycolipid and Unsaturated Fatty Acids in Human Hair

18 citations , August 2014 in “Lipids”

This study found that unsaturated fatty acids are more abundant in the cortex of human hair than on its surface, and steryl glycoside-like lipids may help bind the cuticle to the cortex.

research Molecular Modeling of Hair Keratin/Peptide Complex: Using MM-PBSA Calculations to Describe Experimental Binding Results

14 citations , January 2012 in “Proteins”

This study's molecular dynamics simulations suggest that electrostatic interactions mainly stabilize peptide binding to human hair keratin, with the protein's dielectric constant significantly affecting free energy calculations.

research A Systematic Method for the Sensitive and Specific Determination of Hair Lipids Using Chromatography

43 citations , July 2005 in “Journal of Chromatography B”

This study developed a sensitive method to precisely determine hair lipid composition, demonstrating specific lipid changes from the root to the tip in untreated hair fibers from two women.