Image

    Molecular Modeling of Hair Keratin/Peptide Complex: Using MM-PBSA Calculations to Describe Experimental Binding Results

    January 2012 in “ Proteins ”
    Nuno G. Azóia, Margarida M. Fernandes, Nuno M. Micaêlo … Artur Cavaco‐Paulo
    Studysummary This study's molecular dynamics simulations suggest that electrostatic interactions mainly stabilize peptide binding to human hair keratin, with the protein's dielectric constant significantly affecting free energy calculations.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
    Read the full study on repositorium.sdum.uminho.pt →
    Discuss this study in the Community →

    Research cited in this study 6

    1. Three-Dimensional Modelling of Interchain Sequence Similarities and Differences in the Coiled-Coil Segments of Keratin Intermediate Filament Heterodimers Highlight Features Important in Assembly Journal of Structural Biology · 2007
    2. Structural Stability of Wild Type and Mutated Alpha-Keratin Fragments: Molecular Dynamics and Free Energy Calculations Biomacromolecules · 2004
    3. Multiscale Modelling of Human Hair Philosophical Transactions of the Royal Society A Mathematical Physical and Engineering Sciences · 2004
    4. Hair Care Products: Waving, Straightening, Conditioning, and Coloring Clinics in dermatology · 2001
    5. Hair Care and Hair Care Products Clinics in dermatology · 2001
    6. Hair: Its Structure and Response to Cosmetic Preparations Clinics in dermatology · 1996

    Related research 1

    1. The Extraction And Characterization Of Human Nail Keratin Journal of Dermatological Science · 1991