October 2024 in “Dermatologic Surgery” This study reviewed recent literature and reported that although PRP products are recognized for benefits in dermatology, including wound care and hair growth, there remains a need for standardized protocols and consensus to enhance their acceptance in cosmetic dermatology.
October 2024 in “BMC Genomics” This study examined the cytodifferentiation stage of hair follicle development in cashmere goats, identifying nine cell populations and key regulatory pathways, including transcription factors and keratin genes, that may influence fiber quality and inform breeding strategies.
May 2024 in “Pharmacia/Farmaciâ” In this study, Ipomoea batatas leaf extracts exhibited significant hair growth stimulation and strong antifungal activity against Malassezia furfur, potentially offering a promising treatment for alopecia with further research needed on their androgen receptor inhibition potential.
This study identified seven new compounds from the plant Sansevieria trifasciata Prain and predicted that four of them may have better anti-alopecia activity than minoxidil through an in silico approach.
March 2025 in “SKIN The Journal of Cutaneous Medicine” This study found that most TikTok content on platelet-rich plasma is created by laypeople and non-physician health care providers, and overall video quality is very poor, with content from dermatologists and physicians scoring higher.
January 2025 in “BioMed Research International” This study highlights the role of abnormal DNA methylation in skin disorders such as atopic dermatitis and psoriasis, suggesting these epigenetic changes may serve as biomarkers and targets for potential treatments.
April 2024 in “Journal of clinical medicine” This review discusses the diverse cutaneous manifestations of lupus erythematosus and emphasizes the importance of differential diagnosis for effective management, but reports no new clinical findings.
January 2019 in “Deleted Journal” This in vitro study suggests that Biofield Energy Healing Treatment may promote hair growth as evidenced by increased telogen formation in vibrissae hair follicle organ culture cells.
19 citations
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July 2019 in “Biomedical Microdevices” This review discusses the safety and potential adverse events of microneedling as both a medical and consumer product, noting the need for further understanding; no new clinical results are presented.
18 citations
,
June 2019 in “Clinical research in dermatology” This review discusses psychological impacts associated with facial acne, noting that high levels of anxiety and depression among these patients are not linked to oxidative stress, and reports no new clinical results.
May 2024 in “International journal of molecular sciences” This review synthesizes evidence on platelet-derived bioproducts like PRP and PRF, highlighting their role in tissue regeneration and their benefits in aesthetic medicine applications such as hair restoration, scar treatment, and wound healing.
April 2024 in “Cosmetics” This review highlights the use of microneedling devices and patches to deliver cosmetic agents through the skin, noting their applications in skin rejuvenation and safety considerations such as potential skin irritation and infection.
848 citations
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October 2020 in “International Journal of Molecular Sciences” This review discusses the potential of platelet-rich plasma applications in regenerative medicine and explores recent progress and challenges in translating non-clinical PRP findings into human treatments, but reports no new clinical results.
733 citations
,
September 2009 in “Journal of Cell Science” This article reviews the complex process of wound repair, emphasizing recent microarray studies and proteomic analyses, but reports no new clinical results.
222 citations
,
August 2009 in “Experimental Dermatology” This review discusses the role of stem cells in cutaneous wound healing and reports no clinical results; the authors highlight the need for better understanding of underlying mechanisms for future therapies.
164 citations
,
February 2019 in “Anais Brasileiros de Dermatologia” This study produced a guide for managing adult female acne, addressing its complex nature compared to teenage acne, and providing detailed recommendations on diagnosis and treatment. The authors noted that further research is needed to better understand the condition.
77 citations
,
June 2002 in “Journal of Investigative Dermatology” CD44 variant changes start alopecia areata, but don't maintain it.
72 citations
,
November 2017 in “Journal of developmental biology” This review discusses the role of Hedgehog signaling in epidermal and hair follicle development and its involvement in basal cell carcinoma, without reporting new empirical findings.
71 citations
,
January 2011 in “Journal of cutaneous pathology” This case report describes the first confirmed instance of trichodysplasia spinulosa in a child with Down syndrome and leukemia, linking it to the TS-associated polyomavirus.
54 citations
,
January 2023 in “Signal Transduction and Targeted Therapy” This review examines integrins as pharmacological targets, discussing current integrin-based therapies and emphasizing the need to understand integrin mechanisms for successful drug development, without reporting new clinical results.
37 citations
,
December 2022 in “Acta Pharmaceutica Sinica B” This review discusses the strategies and potential of CRISPR delivery for gene therapy, highlighting the challenges and innovative use of stimuli-responsive nanocarriers, but reports no new experimental results.
37 citations
,
December 2020 in “Molecules” This study reported that a newly formulated Curcumin-loaded proniosome, named F5, exhibited enhanced antiviral efficacy, stability, and safety when compared to Curcumin alone, and improved the therapeutic performance of Acyclovir by reducing its effective dose against Herpes simplex virus.
35 citations
,
February 2024 in “Science Advances” This study introduces a magnet-assisted fabrication strategy for creating complex 3D soft bioscaffolds, demonstrating its effectiveness by producing structures with overhangs and supporting biohybrid actuators, promising advancements in biomedical applications.
25 citations
,
March 2021 in “Australasian Journal of Dermatology” This case study reports a 70-year-old man with treatment-resistant pityriasis rubra pilaris achieving complete clinical remission with ustekinumab, adding to evidence supporting biologic therapy when TNF inhibitors are unsuitable.
24 citations
,
July 2021 in “Pharmaceutics” This article reviews the JAK signaling pathway and the development of ruxolitinib cream as a targeted treatment for inflammatory skin diseases, reporting no new clinical results.
22 citations
,
November 2023 in “Molecules” This review focuses on recent advances in smart responsive polymer microneedles, which offer precise, on-demand drug delivery triggered by external or physiological stimuli, highlighting significant research implications for transdermal drug administration according to this source.
21 citations
,
January 2022 in “Biomaterials Science” This article reviews CRISPR/Cas system delivery methods for genome editing and highlights RNA's promise in non-viral in vivo applications but reports no new clinical results.
21 citations
,
May 2016 in “Experimental and Therapeutic Medicine” In this study, the researchers observed that MMP-2 and MMP-9 significantly fluctuated with the hair growth cycle in mice, suggesting their important role in hair development.
20 citations
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December 2021 in “Plants” This review concludes that Tamarix aphylla, used traditionally for ailments such as tuberculosis and hepatitis, demonstrates various pharmacological activities, including antidiabetic and wound-healing effects, but stresses the need for further research to confirm its safety and effectiveness in humans.
17 citations
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October 2023 in “Polymers” This review highlights advancements in electrospun nanofibers, focusing on their potential applications in biomedical technologies, chemical and biological sensing, and energy harvesting within IoT devices.